Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.45 |
| ▸ | FFAR4 | Q5NUL3 | 6/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.35 |
| ▸ | TACR1 | P25103 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | BTN3A1 | O00481 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9038980 | 0.86 | BACE1 (0.42) | BACE1POLBMAPTL3MBTL1ALDH1A1 | |
| SCHEMBL6965774 | 0.76 | POLB (0.46) | BACE1POLBL3MBTL1ALDH1A1CYP2D6 | |
| SCHEMBL6673753 | 0.76 | BACE1 (0.49) | BACE1ALDH1A1TSHRCYP2C9LMNA | |
| SCHEMBL31094071 | 0.76 | BACE1 (0.49) | BACE1ALDH1A1TSHRCYP2C9LMNA | |
| SCHEMBL8535827 | 0.74 | BACE1 (0.43) | BACE1TACR1BTN3A1 | |
| SCHEMBL6954167 | 0.72 | GABRA1 (0.43) | FFAR4POLBTSHRCYP2D6CYP2C9 | |
| SCHEMBL6966115 | 0.72 | POLB (0.43) | POLBL3MBTL1 | |
| SCHEMBL2769611 | 0.71 | IDO1 (0.53) | BACE1ALDH1A1TSHRCYP2D6 | |
| SCHEMBL2750402 | 0.71 | BACE1 (0.47) | BACE1TACR1MAPT | |
| SCHEMBL31371104 | 0.71 | IDO1 (0.53) | BACE1ALDH1A1TSHRCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5808062-A | AIDS THERAPY | WARNER-LAMBERT COMPANY (US) | 1998-09-15 | — | — | US | claimed |