SCHEMBL8535849

SCHEMBL8535849

CC(C)COC(=O)CCN(CCCCCCN(CCC(=O)OCC(C)C)C1CC(C)(C)NC(C)(C)C1)C1CC(C)(C)NC(C)(C)C1

nearest known ligand 0.40

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 1/20 0.40
MAPT P10636 1/20 0.32
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31
POLB P06746 1/20 0.30
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8534785 0.86 LMNA (0.40) EPHX2ALDH1A1LMNAGAA
SCHEMBL8535439 0.86 EPHX2 (0.36) EPHX2ALDH1A1LMNAPOLBGAA
SCHEMBL8535940 0.84 EPHX2 (0.39) EPHX2ALDH1A1
SCHEMBL8949235 0.83 CYP3A4 (0.51) ALDH1A1LMNA
SCHEMBL8433528 0.83 MEN1 (0.38) EPHX2ALDH1A1LMNAPOLBGAA
SCHEMBL8532522 0.82 EPHX2 (0.40) EPHX2
SCHEMBL8530800 0.81 EPHX2 (0.42) EPHX2
SCHEMBL8535963 0.81 EPHX2 (0.42) EPHX2
SCHEMBL8534959 0.81 EPHX2 (0.42) EPHX2
SCHEMBL8534520 0.81 EPHX2 (0.42) EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5714612-A LIGHT STABILIZATION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-02-03 US disclosed
US-5506286-A BLENDING STABILZER WITH SYNTHETIC RESINS, RUBBERS, PAINTS, OILS TO STABILIZE FROM PHOTOOXIDATION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-04-09 US disclosed
US-5384348-A Improved photostability for polymers, weather resistance SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1995-01-24 US disclosed