Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | HTR2B | P41595 | 2/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.34 |
| ▸ | HTR3A | P46098 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | CASR | P41180 | 2/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.33 |
| ▸ | SHBG | P04278 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8585298 | 0.83 | ESR1 (0.43) | ATMMAPTGPR84KDM4EMAOB | |
| SCHEMBL7371787 | 0.81 | MAPK1 (0.37) | ATMPTGS2MAPTHTR2BGPR84 | |
| SCHEMBL6965244 | 0.80 | ALOX5 (0.38) | PTGS2MAPTGPR84KDM4E | |
| SCHEMBL6960622 | 0.80 | SMN1; SMN2 (0.49) | PTGS2MAPTGPR84KDM4EALDH1A1 | |
| SCHEMBL6952786 | 0.79 | L3MBTL1 (0.39) | PTGS2MAPTHTR2BGPR84HTR3A | |
| SCHEMBL11787842 | 0.78 | ALDH1A1 (0.45) | PTGS2MAPTHTR2BGPR84HTR3A | |
| SCHEMBL6959678 | 0.78 | SMN1; SMN2 (0.42) | MAPTHTR2BGPR84HTR3AKDM4E | |
| SCHEMBL6958994 | 0.78 | HPGD (0.45) | ATMMAPTKDM4EALDH1A1CNR2 | |
| SCHEMBL6954657 | 0.77 | SMN1; SMN2 (0.44) | MAPTHTR2BGPR84HTR3AKDM4E | |
| SCHEMBL6965249 | 0.77 | HCAR2 (0.40) | MAPTGPR84KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5808062-A | AIDS THERAPY | WARNER-LAMBERT COMPANY (US) | 1998-09-15 | — | — | US | claimed |
| US-5808062-A | AIDS THERAPY | WARNER-LAMBERT COMPANY (US) | 1998-09-15 | — | — | US | disclosed |