Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 12/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 9/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.45 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CTSD | P07339 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL625374 | 0.93 | SLC6A4 (0.47) | SLC6A4SLC6A3SLC6A2PIM1PIM2 | |
| SCHEMBL22816524 | 0.88 | MMP1 (0.41) | SLC6A4SLC6A3SLC6A2PIM1PIM2 | |
| SCHEMBL28888791 | 0.82 | SLC6A4 (0.49) | SLC6A4SLC6A3SLC6A2PIM1PIM2 | |
| SCHEMBL4554666 | 0.77 | SLC6A4 (0.44) | SLC6A4SLC6A3SLC6A2PIM1PIM2 | |
| SCHEMBL23270140 | 0.76 | SLC6A4 (0.42) | SLC6A4SLC6A3SLC6A2PIM1PIM2 | |
| SCHEMBL23270139 | 0.76 | SLC6A4 (0.42) | SLC6A4SLC6A3SLC6A2PIM1PIM2 | |
| SCHEMBL1954322 | 0.76 | ALDH1A1 (0.47) | SLC6A4SLC6A3SLC6A2PIM1PIM2 | |
| SCHEMBL12047029 | 0.76 | MAOA (0.44) | SLC6A4SLC6A3SLC6A2PIM1PIM2 | |
| SCHEMBL8532718 | 0.75 | SLC6A4 (0.47) | SLC6A4KMT2ACTSDBACE1BACE2 | |
| SCHEMBL19955250 | 0.75 | SLC6A4 (0.43) | SLC6A4SLC6A3SLC6A2PIM1PIM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021078995-A1 | SELECTIVE POLYPEPTIDE SYNTHESIS STALLING ASSAY AND COMPOUND | UMC UTRECHT HOLDING B.V. (NL) | 2021-04-29 | — | — | WO | disclosed |
| EP-3811945-A1 | COMPOUNDS FOR TREATING AND PREVENTING GROWTH HORMONE RECEPTOR-DEPENDENT CONDITIONS | UMC Utrecht Holding B.V. (NL) | 2021-04-28 | — | — | EP | disclosed |
| US-5763700-A | INSECTICIDES | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1998-06-09 | — | — | US | disclosed |
| EP-0660815-B1 | PESTICIDAL FLUOROOLEFINS | BRITISH TECH GROUP (GB) | 1997-04-16 | — | — | EP | disclosed |
| WO-1994006741-A1 | PESTICIDAL FLUOROOLEFINS | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1994-03-31 | — | — | WO | disclosed |