Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | ATF4 | P18848 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6152076 | 0.95 | KMT2A (0.56) | KMT2ARAB9AMEN1KDM4ESMN1; SMN2 | |
| SCHEMBL8535957 | 0.79 | KMT2A (0.64) | KMT2ARAB9AMEN1KDM4ESMN1; SMN2 | |
| SCHEMBL1006629 | 0.74 | ALDH1A1 (0.54) | KMT2ARAB9AMEN1KDM4ESMN1; SMN2 | |
| SCHEMBL15623631 | 0.73 | RXFP1 (0.63) | KMT2ARAB9AMEN1KDM4ESMN1; SMN2 | |
| SCHEMBL11851882 | 0.71 | RAB9A (0.68) | KMT2ARAB9AMEN1KDM4ESMN1; SMN2 | |
| SCHEMBL342739 | 0.71 | NOTUM (1.00) | KMT2ARAB9AMEN1KDM4ESMN1; SMN2 | |
| SCHEMBL27633763 | 0.70 | MAPT (0.73) | RAB9AKDM4ESMN1; SMN2CYP3A4ALDH1A1 | |
| SCHEMBL27654972 | 0.70 | NOX1 (0.56) | KMT2ARAB9AMEN1KDM4ESMN1; SMN2 | |
| SCHEMBL27633944 | 0.70 | CYP1A2 (0.69) | KMT2ARAB9AMEN1KDM4ESMN1; SMN2 | |
| SCHEMBL2730327 | 0.70 | KMT2A (0.67) | KMT2ANOTUMLMNACYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1497281-A4 | AZOLE DERIVATIVES AS ANTIFUNGAL AGENTS | RANBAXY LAB LTD (IN) | 2005-11-02 | — | — | EP | disclosed |
| US-20050131041-A1 | Azole derivatives as antifungal agents | RANBAXY LABORATORIES LIMITED (IN) | 2005-06-16 | — | — | US | disclosed |
| EP-1497281-A2 | AZOLE DERIVATIVES AS ANTIFUNGAL AGENTS | RANBAXY LABORATORIES, LTD. (IN) | 2005-01-19 | — | — | EP | disclosed |
| WO-2003086271-A2 | AZOLE DERIVATIVES AS ANTIFUNGAL AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2003-10-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050131041-A1 | Azole derivatives as antifungal agents | ERG28, CYP51A1, CYP3A7 | KMT2A 3684/4885RAB9A 3296/4885MEN1 636/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.