Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTP1 | P09211 | 2/20 | 0.48 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.40 |
| ▸ | F2 | P00734 | 2/20 | 0.40 |
| ▸ | CYP27B1 | O15528 | 1/20 | 0.40 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | IKBKB | O14920 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9047747 | 0.79 | PIK3R1 (0.42) | NPC1HTTSMN1; SMN2 | |
| SCHEMBL6689631 | 0.74 | GSTP1 (0.48) | GSTP1NPC1HTTSMN1; SMN2 | |
| SCHEMBL1957932 | 0.70 | F2 (0.62) | GSTP1MAOBF2NPC1HTT | |
| SCHEMBL28065277 | 0.69 | ESR2 (0.45) | MAOBNPC1SMN1; SMN2CYP19A1 | |
| SCHEMBL4569962 | 0.69 | F2 (0.60) | MAOBF2NPC1HTTSMN1; SMN2 | |
| SCHEMBL812897 | 0.67 | CTRC (0.48) | MAOBHTT | |
| SCHEMBL28254274 | 0.66 | GSTP1 (0.57) | GSTP1MAOBNPC1SMN1; SMN2KCNH2 | |
| SCHEMBL25081229 | 0.66 | PRMT5 (0.45) | MAOBF2CYP27B1CYP24A1NPC1 | |
| SCHEMBL1423718 | 0.66 | IKBKE (0.49) | GSTP1MAOBF2NPC1SMN1; SMN2 | |
| SCHEMBL1423595 | 0.66 | F2 (0.50) | GSTP1MAOBF2NPC1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5808062-A | AIDS THERAPY | WARNER-LAMBERT COMPANY (US) | 1998-09-15 | — | — | US | disclosed |