SCHEMBL812897

SCHEMBL812897

O=c1occcc1-c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTRC Q99895 3/20 0.48
CA1 P00915 1/20 0.46
CA9 Q16790 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
TSHR P16473 1/20 0.46
HDAC4 P56524 1/20 0.43
HDAC2 Q92769 1/20 0.43
HDAC8 Q9BY41 1/20 0.43
HDAC6 Q9UBN7 1/20 0.43
ALDH1A1 P00352 7/20 0.41
HTT P42858 2/20 0.41
KDM4E B2RXH2 2/20 0.41
POLB P06746 1/20 0.41
MAPT P10636 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
MAOB P27338 1/20 0.41
RAB9A P51151 1/20 0.41
SMARCA2 P51531 1/20 0.40
PBRM1 Q86U86 1/20 0.40
MGLL Q99685 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Naphthalene SCHEMBL29025700 0.94 KDM4E (0.46) CTRCCA1CA9NPSR1TSHR
SCHEMBL28065277 0.81 ESR2 (0.45) TSHRHDAC6ALDH1A1KDM4EPOLB
SCHEMBL9047747 0.81 PIK3R1 (0.42) CA1CA9TSHRALDH1A1HTT
SCHEMBL2398844 0.81 KEAP1 (0.44) CA1CA9TSHRHDAC4HDAC2
SCHEMBL6689631 0.79 GSTP1 (0.48) CA1CA9NPSR1TSHRHDAC4
SCHEMBL25372606 0.74 LMNA (0.44) CTRCCA1CA9HDAC4HDAC2
SCHEMBL8088273 0.74 MAOB (0.47) ALDH1A1MAOBCYP2A6PKM
SCHEMBL7116127 0.73 KDM4E (0.51) TSHRALDH1A1KDM4EPOLBMAPT
SCHEMBL29755699 0.73 KDM4E (0.51) TSHRALDH1A1KDM4EPOLBMAPT
SCHEMBL2287130 0.72 APP (0.57) MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 190 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116124746-A Application of naphthobenzopyrone fluorescent probe in detection of mercury ions, iron ions and iodide ions 甘肃中医药大学 2023-05-16 CN claimed
CN-111333661-A Phenylpyrone derivative of Phellinus ribis, and preparation method and application thereof 吴浩然 2020-06-26 CN claimed
EP-1280770-B1 C 2? PHENYL-SUBSTITUTED CYCLIC KETO-ENOLS USED AS PESTICIDES AND HERBICIDES BAYER AG (DE) 2010-06-23 EP claimed
EP-1123003-B1 UTILIZATION OF 3-PHENYL-PYRONES FOR PEST CONTROL BAYER CROPSCIENCE AG (DE) 2004-03-17 EP claimed
EP-1119559-B1 3-PHENYL-PYRONES BAYER CROPSCIENCE AG (DE) 2003-11-26 EP claimed
US-20030216260-A1 C2-phenyl-substituted cyclic keto-enols used as pesticides and herbicides BAYER INTELLECTUAL PROPERTY GMBH (DE) 2003-11-20 US claimed
US-6472350-B1 Utilization of 3-phenyl-pyrones for pest control BAYER AKTIENGESELLSCHAFT (DE) 2002-10-29 US claimed
US-6441030-B1 PESTICIDES, FUNGICIDES AND HERBICIDES BAYER AKTIENGESELLSCHAFT (DE) 2002-08-27 US claimed
EP-1123003-A1 UTILIZATION OF 3-PHENYL-PYRONES FOR PEST CONTROL Bayer Aktiengesellschaft (DE) 2001-08-16 EP claimed
EP-1119559-A1 3-PHENYL-PYRONES Bayer Aktiengesellschaft (DE) 2001-08-01 EP claimed
WO-2000024256-A1 UTILIZATION OF 3-PHENYL-PYRONES FOR PEST CONTROL BAYER AKTIENGESELLSCHAFT (DE) 2000-05-04 WO claimed
WO-2000021946-A1 3-PHENYL-PYRONES BAYER AKTIENGESELLSCHAFT (DE) 2000-04-20 WO claimed
US-20250002487-A1 HETEROCYCLIC COMPOUNDS AND USES THEREOF VENTUS THERAPEUTICS U.S., INC. (US) 2025-01-02 US disclosed
CN-114588187-B Traditional Chinese medicine total flavone extract for treating cataract, and composition, preparation method and medical application thereof 赣江新区艾泽生物医药科技有限公司 2023-08-11 CN disclosed
CN-114588187-A Traditional Chinese medicine total flavone extract for treating cataract, composition thereof, preparation method and medical application 赣江新区艾泽生物医药科技有限公司 2022-06-07 CN disclosed
CN-111333661-A Phenylpyrone derivative of Phellinus ribis, and preparation method and application thereof 吴浩然 2020-06-26 CN disclosed
CN-1225092-A Novel substituted pyridyl keto enols BAYER AG (DE) 1999-08-04 CN disclosed
CN-1207737-A Oxymethoxy-3-aryl-pyrone derivs. BAYER AG (DE) 1999-02-10 CN disclosed
CN-1173866-A 2 -phenyl -substituted heterocyclic 1, 3 -keonols as herbicides and pesticides BAYER AG (DE) 1998-02-18 CN disclosed
US-5393729-A Pesticides, fungicides, herbicides BAYER AKTIENGESELLSCHAFT (DE) 1995-02-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030216260-A1 C2-phenyl-substituted cyclic keto-enols used as pesticides and herbicides PDHX, AKR1C3, AKR1A1 CTRC 476/4885CA1 295/4885CA9 642/4885
US-20250002487-A1 HETEROCYCLIC COMPOUNDS AND USES THEREOF CGAS, TDP1, CYP11B2 CTRC 1391/4885CA1 595/4885CA9 538/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.