Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3R1 | P27986 | 1/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.42 |
| ▸ | CFTR | P13569 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL812897 | 0.81 | CTRC (0.48) | RAB9ATSHRMAPTALDH1A1HSD17B10 | |
| SCHEMBL8535966 | 0.79 | GSTP1 (0.48) | SMN1; SMN2NPC1HTT | |
| Naphthalene SCHEMBL29025700 | 0.76 | KDM4E (0.46) | PIK3R1PIK3CASMN1; SMN2NPC1RAB9A | |
| SCHEMBL28065277 | 0.76 | ESR2 (0.45) | CFTRSMN1; SMN2NPC1RAB9ATSHR | |
| SCHEMBL6689631 | 0.74 | GSTP1 (0.48) | SMN1; SMN2NPC1RAB9ATSHRMAPT | |
| SCHEMBL8088273 | 0.73 | MAOB (0.47) | PIK3CAALDH1A1ADORA2AADORA1PIK3CD | |
| SCHEMBL2398844 | 0.72 | KEAP1 (0.44) | SMN1; SMN2NPC1RAB9ATSHRMAPT | |
| SCHEMBL4032281 | 0.70 | NOTUM (0.63) | SMN1; SMN2NPC1RAB9ATSHRMAPT | |
| SCHEMBL30708901 | 0.70 | NOTUM (0.63) | SMN1; SMN2NPC1RAB9ATSHRMAPT | |
| SCHEMBL12440870 | 0.70 | NPC1 (0.59) | PIK3R1PIK3CACFTRSMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117425654-A | 2, 8-diazaspiro [4.5] decane compounds | 基因泰克公司 | 2024-01-19 | — | — | CN | disclosed |
| EP-0729464-A1 | 5,6-DIHYDROPYRONE DERIVATIVES AS PROTEASE INHIBITORS AND ANTIVIRAL AGENTS | PARKE, DAVIS & COMPANY (US) | 1996-09-04 | — | — | EP | disclosed |