Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | GLA | P06280 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | PTPRC | P08575 | 1/20 | 0.35 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.35 |
| ▸ | PTPN9 | P43378 | 1/20 | 0.35 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.35 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.35 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8533753 | 0.92 | KDM4E (0.34) | KDM4EALDH1A1HPGDGAAGLA | |
| SCHEMBL6957097 | 0.77 | CYSLTR1 (0.41) | PTPRCPTPN2PTPN1PTPN6PTPN9 | |
| SCHEMBL8539946 | 0.77 | MCL1 (0.38) | KDM4EALDH1A1HPGDHSD17B10MAPK1 | |
| SCHEMBL8585298 | 0.76 | ESR1 (0.43) | KDM4EHPGDGAAGLANPSR1 | |
| SCHEMBL6959687 | 0.75 | POLB (0.38) | PTPRCPTPN2PTPN1PTPN6PTPN9 | |
| SCHEMBL8535874 | 0.75 | ATM (0.36) | KDM4EALDH1A1CA12CA1CA2 | |
| SCHEMBL6955817 | 0.74 | MAOB (0.45) | KDM4EALDH1A1HPGDMAPK1SMN1; SMN2 | |
| SCHEMBL6960622 | 0.73 | SMN1; SMN2 (0.49) | KDM4EALDH1A1HPGDHSD17B10MAPK1 | |
| SCHEMBL6952786 | 0.72 | L3MBTL1 (0.39) | KDM4EALDH1A1MAPK1CA12CA1 | |
| SCHEMBL8534507 | 0.72 | KDM4E (0.40) | KDM4EALDH1A1HPGDGAAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5808062-A | AIDS THERAPY | WARNER-LAMBERT COMPANY (US) | 1998-09-15 | — | — | US | disclosed |