Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8535971 | 0.92 | KDM4E (0.36) | KDM4EALDH1A1HPGDGLAGAA | |
| SCHEMBL8534507 | 0.79 | KDM4E (0.40) | KDM4EALDH1A1HPGDGAANPSR1 | |
| SCHEMBL6957097 | 0.75 | CYSLTR1 (0.41) | MAPTL3MBTL1SMN1; SMN2 | |
| SCHEMBL8585298 | 0.74 | ESR1 (0.43) | KDM4EHPGDGLAGAANPSR1 | |
| SCHEMBL6965449 | 0.74 | PTGER4 (0.39) | KDM4EALDH1A1HPGDNPSR1HSD17B10 | |
| SCHEMBL6959687 | 0.73 | POLB (0.38) | MAPTTDP1L3MBTL1FAAHSMN1; SMN2 | |
| SCHEMBL8535874 | 0.73 | ATM (0.36) | KDM4EALDH1A1MAPT | |
| SCHEMBL9039893 | 0.73 | LMNA (0.43) | KDM4EALDH1A1HPGDGAAMAPT | |
| SCHEMBL6955817 | 0.72 | MAOB (0.45) | KDM4EALDH1A1HPGDMAPK1MAPT | |
| SCHEMBL8533751 | 0.72 | KDM4E (0.35) | KDM4EALDH1A1HPGDNPSR1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5808062-A | AIDS THERAPY | WARNER-LAMBERT COMPANY (US) | 1998-09-15 | — | — | US | claimed |
| US-5808062-A | AIDS THERAPY | WARNER-LAMBERT COMPANY (US) | 1998-09-15 | — | — | US | disclosed |