Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | CTSG | P08311 | 1/20 | 0.35 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.35 |
| ▸ | CMA1 | P23946 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8536105 | 0.81 | POLB (0.41) | POLBALDH1A1KDM4ERIPK1HTR2A | |
| Water SCHEMBL11427319 | 0.80 | POLB (0.40) | POLBALDH1A1KDM4ERIPK1HTR2A | |
| Hydrochloric Acid SCHEMBL11127650 | 0.80 | POLB (0.40) | POLBALDH1A1KDM4ERIPK1HTR2A | |
| SCHEMBL8322227 | 0.79 | POLB (0.39) | POLBALDH1A1KDM4ERIPK1HTR2A | |
| SCHEMBL7760569 | 0.78 | POLB (0.41) | POLBALDH1A1KDM4EHTR2AHRH1 | |
| SCHEMBL705080 | 0.77 | CTSK (0.40) | POLBALDH1A1KDM4ERIPK1HTR2A | |
| SCHEMBL28357908 | 0.77 | POLB (0.41) | POLBALDH1A1KDM4ERIPK1HTR2A | |
| SCHEMBL11307941 | 0.76 | POLB (0.40) | POLBALDH1A1KDM4EHTR2AHRH1 | |
| SCHEMBL8159106 | 0.76 | POLB (0.47) | POLBALDH1A1KDM4EHTR2AHRH1 | |
| Hydrochloric Acid SCHEMBL11129021 | 0.75 | POLB (0.39) | POLBALDH1A1KDM4EHTR2AHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0480052-B1 | QUINOLINE DERIVATIVE, ANTIULCER DRUG CONTAINING THE SAME, AND PRODUCTION OF SAID DERIVATIVE | OTSUKA PHARMA CO LTD (JP) | 1998-01-14 | — | — | EP | disclosed |
| US-5215999-A | Quinoline derivative and antiulcer agent containing said quinoline derivative | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-06-01 | — | — | US | disclosed |
| EP-0480052-A1 | QUINOLINE DERIVATIVE, ANTIULCER DRUG CONTAINING THE SAME, AND PRODUCTION OF SAID DERIVATIVE | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1992-04-15 | — | — | EP | disclosed |