Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 12/20 | 0.35 |
| ▸ | CA2 | P00918 | 12/20 | 0.35 |
| ▸ | CA4 | P22748 | 3/20 | 0.35 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.35 |
| ▸ | HSD17B2 | P37059 | 3/20 | 0.35 |
| ▸ | CA9 | Q16790 | 7/20 | 0.34 |
| ▸ | CA12 | O43570 | 6/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | TMPRSS6 | Q8IU80 | 1/20 | 0.32 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.32 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.32 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.32 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.31 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.31 |
| ▸ | ITGAV | P06756 | 1/20 | 0.31 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.31 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.31 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8499997 | 0.74 | PFKFB3 (0.41) | CA1CA2HSD17B1HSD17B2MAPT | |
| SCHEMBL8697026 | 0.72 | CA1 (0.40) | CA1CA2CA4CA9CA12 | |
| SCHEMBL8532207 | 0.72 | CA1 (0.33) | CA1CA2CA4CA9CA12 | |
| SCHEMBL8531518 | 0.70 | CA1 (0.34) | CA1CA2CA4CA9CA12 | |
| SCHEMBL8536202 | 0.69 | FFAR1 (0.35) | CA1CA2CA4CA9CA12 | |
| SCHEMBL8429166 | 0.68 | CA1 (0.43) | CA1CA2CA4HSD17B1HSD17B2 | |
| SCHEMBL8501213 | 0.64 | CA12 (0.40) | CA1CA2CA9CA12ITGB3 | |
| SCHEMBL8693780 | 0.64 | CA1 (0.39) | CA1CA2CA4HSD17B1HSD17B2 | |
| SCHEMBL8499992 | 0.64 | MEN1 (0.42) | CA1CA2HSD17B1HSD17B2MAPT | |
| SCHEMBL8694027 | 0.63 | CA1 (0.38) | CA1CA2CA4HSD17B1HSD17B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773646-A | INTEGRIN INHIBITORS | G. D. SEARLE & CO. (US) | 1998-06-30 | — | — | US | disclosed |