SCHEMBL8536148

SCHEMBL8536148

COC(=O)CCN(CCCCCCN(CCC(=O)OC)C1CC(C)(C)N(C)C(C)(C)C1)C1CC(C)(C)N(C)C(C)(C)C1

nearest known ligand 0.37

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KDM5A P29375 2/20 0.37
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
TSHR P16473 3/20 0.34
EPHX2 P34913 3/20 0.34
GLA P06280 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.32
CNR1 P21554 1/20 0.31
CNR2 P34972 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
ALDH1A1 P00352 2/20 0.30
LMNA P02545 1/20 0.30
FPR3 P25089 1/20 0.30
FPR2 P25090 1/20 0.30
PKM P14618 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8949243 0.89 MEN1 (0.33) MEN1KMT2ASMN1; SMN2
SCHEMBL8530966 0.89 MEN1 (0.37) KDM5AMEN1KMT2ATSHREPHX2
SCHEMBL8433528 0.82 MEN1 (0.38) KDM5AMEN1KMT2ATSHREPHX2
SCHEMBL8949112 0.81 GAA (0.34)
SCHEMBL8949295 0.81 GAA (0.32) MEN1KMT2A
SCHEMBL13160743 0.80 KDM5A (0.33) KDM5A
SCHEMBL8533073 0.80 KDM5A (0.39) KDM5AMEN1KMT2AEPHX2
SCHEMBL11407691 0.79 KDM5A (0.39) KDM5AMEN1KMT2ATSHRALDH1A1
SCHEMBL13160765 0.79 KDM5A (0.32) KDM5A
SCHEMBL13160741 0.76 KDM1A (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5714612-A LIGHT STABILIZATION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-02-03 US claimed
US-5384348-A Improved photostability for polymers, weather resistance SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1995-01-24 US claimed
US-5714612-A LIGHT STABILIZATION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-02-03 US disclosed
US-5506286-A BLENDING STABILZER WITH SYNTHETIC RESINS, RUBBERS, PAINTS, OILS TO STABILIZE FROM PHOTOOXIDATION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-04-09 US disclosed
US-5384348-A Improved photostability for polymers, weather resistance SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1995-01-24 US disclosed