SCHEMBL8533073

SCHEMBL8533073

CCCCCCCCON1C(C)(C)CC(N(CCCCCCN(CCC(=O)OC)C2CC(C)(C)N(OCCCCCCCC)C(C)(C)C2)CCC(=O)OC)CC1(C)C

nearest known ligand 0.39

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KDM5A P29375 2/20 0.39
CA12 O43570 2/20 0.35
CA14 Q9ULX7 2/20 0.35
CA2 P00918 1/20 0.35
CA7 P43166 1/20 0.35
CA9 Q16790 1/20 0.35
EPHX2 P34913 10/20 0.34
DRD3 P35462 1/20 0.32
DNM1 Q05193 1/20 0.32
POLB P06746 1/20 0.32
POLA1 P09884 1/20 0.32
PPARG P37231 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8949286 0.91 NAAA (0.38) KDM5AEPHX2DNM1MEN1KMT2A
SCHEMBL8838269 0.87 KDM5A (0.40) KDM5ACA12CA14CA2CA7
SCHEMBL8530966 0.80 MEN1 (0.37) KDM5AEPHX2MEN1KMT2A
SCHEMBL8536148 0.80 KDM5A (0.37) KDM5AEPHX2MEN1KMT2A
SCHEMBL8838286 0.78 EPHX2 (0.41) EPHX2DNM1
SCHEMBL8838285 0.78 EPHX2 (0.41) EPHX2DNM1
SCHEMBL8917970 0.78 KDM5A (0.36) KDM5AEPHX2PPARGMEN1KMT2A
SCHEMBL9351971 0.76 EPHX2 (0.35) EPHX2
SCHEMBL8838281 0.76 EPHX2 (0.30) EPHX2
SCHEMBL9351981 0.76 EPHX2 (0.36) EPHX2DNM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5714612-A LIGHT STABILIZATION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-02-03 US disclosed
US-5506286-A BLENDING STABILZER WITH SYNTHETIC RESINS, RUBBERS, PAINTS, OILS TO STABILIZE FROM PHOTOOXIDATION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-04-09 US disclosed
US-5384348-A Improved photostability for polymers, weather resistance SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1995-01-24 US disclosed