Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.38 |
| ▸ | EP300 | Q09472 | 1/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3957966 | 0.84 | HCAR2 (0.56) | HCAR2 | |
| SCHEMBL7814443 | 0.81 | PDE4D (0.58) | HCAR2PDE4DMEN1CYP1A2CYP2C19 | |
| SCHEMBL9025697 | 0.81 | KDM4E (0.43) | HCAR2MEN1KMT2ALMNA | |
| SCHEMBL11204973 | 0.81 | KDM4C (0.49) | HCAR2PDE4DCYP1A2TSHRLMNA | |
| SCHEMBL9025654 | 0.77 | HCAR2 (0.40) | HCAR2PDE4DLMNA | |
| SCHEMBL9037584 | 0.77 | HCAR2 (0.36) | HCAR2MEN1KMT2ALMNA | |
| SCHEMBL9026702 | 0.73 | NPC1 (0.44) | — | |
| SCHEMBL9026160 | 0.73 | HCAR2 (0.37) | HCAR2PDE4D | |
| SCHEMBL9026943 | 0.72 | HCAR2 (0.72) | HCAR2KMT2A | |
| SCHEMBL9026200 | 0.71 | CHRNB2 (0.38) | HCAR2PDE4DCYP1A2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0823911-A1 | ESTERS OF CARBAPENEMS | SMITHKLINE BEECHAM PLC (GB) | 1998-02-18 | — | — | EP | disclosed |
| EP-0823910-A1 | ESTERS OF CARBAPENEMS | SMITHKLINE BEECHAM PLC (GB) | 1998-02-18 | — | — | EP | disclosed |
| WO-1996034869-A1 | ESTERS OF CARBAPENEMS | SMITHKLINE BEECHAM PLC (GB) | 1996-11-07 | — | — | WO | disclosed |
| WO-1996034868-A1 | ESTERS OF CARBAPENEMS | SMITHKLINE BEECHAM PLC (GB) | 1996-11-07 | — | — | WO | disclosed |
| EP-0725783-A1 | 2-(PYRAZOL-3-YL)CARBAPENEM DERIVATIVES | SMITHKLINE BEECHAM PLC (GB) | 1996-08-14 | — | — | EP | disclosed |
| WO-1995011905-A1 | 2-(PYRAZOL-3-YL)CARBAPENEM DERIVATIVES | SMITHKLINE BEECHAM PLC (GB) | 1995-05-04 | — | — | WO | disclosed |