SCHEMBL8536711

SCHEMBL8536711

CCCCC[C@H]1CC[C@H](C2(c3cc(F)c(F)c(F)c3)CCCCC2)CC1

nearest known ligand 0.36

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.36
SLC6A2 P23975 4/20 0.34
SLC6A4 P31645 4/20 0.34
SLC6A3 Q01959 4/20 0.34
OPRL1 P41146 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2C8 P10632 1/20 0.31
CYP2D6 P10635 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31
S1PR3 Q99500 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8536712 1.00 CYP1A2 (0.36) CYP1A2SLC6A2SLC6A4SLC6A3OPRL1
SCHEMBL8020936 0.88 SLC6A4 (0.48) CYP1A2SLC6A2SLC6A4SLC6A3OPRL1
SCHEMBL8536568 0.88 SLC6A4 (0.48) CYP1A2SLC6A2SLC6A4SLC6A3OPRL1
SCHEMBL9180980 0.83 SLC6A3 (0.40) CYP1A2SLC6A2SLC6A4SLC6A3OPRL1
SCHEMBL10336534 0.80 CYP1A2 (0.36) CYP1A2SLC6A4SLC6A3OPRL1
SCHEMBL9574554 0.79 OPRL1 (0.33) SLC6A2SLC6A4SLC6A3OPRL1
SCHEMBL9574561 0.79 OPRL1 (0.33) SLC6A2SLC6A4SLC6A3OPRL1
SCHEMBL6524970 0.78 SLC6A4 (0.51) CYP1A2SLC6A2SLC6A4SLC6A3OPRL1
SCHEMBL10652906 0.78 CYP1A2 (0.40) CYP1A2CYP3A4CYP2C8CYP2D6CYP2C9
SCHEMBL8076356 0.77 CCR2 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5762826-A Liquid crystal composition and a liquid crystal display element which contains it SHIN-ETSU CHEMICAL CO., LTD. (JP) 1998-06-09 US disclosed