Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EED | O75530 | 1/20 | 0.37 |
| ▸ | RBBP4 | Q09028 | 1/20 | 0.37 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.37 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.37 |
| ▸ | AEBP2 | Q6ZN18 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.32 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8536606 | 1.00 | EED (0.37) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL8536680 | 0.75 | KDM4E (0.42) | ALDH1A1KDM4EADRA1AADRA1BKDM1A | |
| SCHEMBL8536684 | 0.75 | KDM4E (0.42) | ALDH1A1KDM4EADRA1AADRA1BKDM1A | |
| SCHEMBL12270386 | 0.75 | TSHR (0.42) | ALDH1A1ADRA1AADRA1BHPGDCYP2C19 | |
| SCHEMBL28327206 | 0.71 | ADRA1A (0.40) | ADRA1AADRA1BGPR119MEN1KMT2A | |
| SCHEMBL5476837 | 0.71 | TSHR (0.39) | ALDH1A1ADRA1AADRA1BCYP2C19MEN1 | |
| SCHEMBL27713925 | 0.71 | ADRA1A (0.40) | ALDH1A1KDM4EADRA1AADRA1BMEN1 | |
| SCHEMBL13791900 | 0.71 | GPR119 (0.52) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL109178 | 0.71 | TSHR (0.50) | ALDH1A1ADRA1AADRA1BMEN1KMT2A | |
| SCHEMBL30111657 | 0.71 | TSHR (0.50) | ALDH1A1ADRA1AADRA1BMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885869-A1 | THERAPEUTIC AGENT FOR DIABETES | Japan Tobacco Inc. (JP) | 1998-12-23 | — | — | EP | disclosed |