Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.66 |
| ▸ | HPGD | P15428 | 5/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.66 |
| ▸ | MAPT | P10636 | 4/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.66 |
| ▸ | POLB | P06746 | 3/20 | 0.66 |
| ▸ | MEN1 | O00255 | 3/20 | 0.66 |
| ▸ | GMNN | O75496 | 2/20 | 0.66 |
| ▸ | LMNA | P02545 | 2/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.66 |
| ▸ | BLM | P54132 | 2/20 | 0.66 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.66 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.66 |
| ▸ | CMKLR1 | Q99788 | 2/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.66 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.66 |
| ▸ | TP53 | P04637 | 1/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29875679 | 0.85 | ALDH1A1 (0.70) | ALDH1A1HPGDKDM4EMAPTKMT2A | |
| SCHEMBL1716864 | 0.85 | ALDH1A1 (0.70) | ALDH1A1HPGDKDM4EMAPTKMT2A | |
| SCHEMBL29387947 | 0.84 | ALDH1A1 (0.63) | ALDH1A1HPGDKDM4EMAPTKMT2A | |
| SCHEMBL4707024 | 0.84 | PTPN1 (0.62) | ALDH1A1HPGDKDM4EMAPTKMT2A | |
| SCHEMBL818033 | 0.84 | ALDH1A1 (0.63) | ALDH1A1HPGDKDM4EMAPTKMT2A | |
| SCHEMBL6008188 | 0.81 | ALDH1A1 (0.65) | ALDH1A1HPGDKDM4EMAPTKMT2A | |
| SCHEMBL10416279 | 0.81 | ALDH1A1 (0.65) | ALDH1A1HPGDKDM4EMAPTKMT2A | |
| SCHEMBL29875233 | 0.81 | ALDH1A1 (0.64) | ALDH1A1HPGDKDM4EMAPTKMT2A | |
| SCHEMBL2843776 | 0.81 | ALDH1A1 (0.64) | ALDH1A1HPGDKDM4EMAPTKMT2A | |
| SCHEMBL10358075 | 0.80 | ALDH1A1 (0.63) | ALDH1A1HPGDKDM4EMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885869-A1 | THERAPEUTIC AGENT FOR DIABETES | Japan Tobacco Inc. (JP) | 1998-12-23 | — | — | EP | disclosed |