Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.67 |
| ▸ | CASP7 | P55210 | 1/20 | 0.67 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TERT | O14746 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.33 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31403341 | 0.80 | ALDH1A1 (1.00) | ALDH1A1HSD17B10CYP1A2ALOX15CASP7 | |
| SCHEMBL13498773 | 0.80 | ALDH1A1 (1.00) | ALDH1A1HSD17B10CYP1A2ALOX15CASP7 | |
| SCHEMBL31123471 | 0.78 | ALDH1A1 (0.70) | ALDH1A1HSD17B10CYP1A2ALOX15CASP7 | |
| SCHEMBL23642752 | 0.76 | ALDH1A1 (0.67) | ALDH1A1HSD17B10CYP1A2ALOX15CASP7 | |
| SCHEMBL11817518 | 0.73 | ALDH1A1 (0.42) | ALDH1A1HSD17B10CYP1A2ALOX15CASP7 | |
| SCHEMBL985209 | 0.73 | MAPT (0.37) | ALDH1A1HSD17B10CYP1A2ALOX15CASP7 | |
| SCHEMBL30385983 | 0.73 | MAPT (0.37) | ALDH1A1HSD17B10CYP1A2ALOX15CASP7 | |
| SCHEMBL5694433 | 0.73 | ALDH1A1 (0.61) | ALDH1A1HSD17B10CYP1A2ALOX15CASP7 | |
| SCHEMBL439013 | 0.73 | CYP3A4 (0.80) | ALDH1A1HSD17B10CYP1A2ALOX15CASP7 | |
| SCHEMBL8540634 | 0.71 | L3MBTL1 (0.47) | ALDH1A1HSD17B10CYP3A4TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0591059-B1 | Use of sulfur-containing metaphenylenediamines for dyeing keratinic fibers and new sulfur-containing metaphenylenediamines | OREAL (FR) | 1998-04-15 | — | — | EP | claimed |