Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A3 | P47895 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TYR | P14679 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 2/20 | 0.34 |
| ▸ | ACHE | P22303 | 2/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.34 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylene SCHEMBL6226363 | 0.93 | LMNA (0.48) | ALDH1A3LMNATYRALDH1A1ALDH3A1 | |
| Ethylene SCHEMBL8585970 | 0.85 | TYR (0.46) | ALDH1A3LMNATYRALDH1A1ALDH3A1 | |
| Ethylene SCHEMBL8532842 | 0.85 | LMNA (0.41) | ALDH1A3LMNATYRALDH1A1ALDH3A1 | |
| Benzaldehyde SCHEMBL11346796 | 0.84 | ALDH1A1 (0.50) | ALDH1A3LMNATYRALDH1A1ALDH3A1 | |
| Cyclopropane SCHEMBL6228970 | 0.84 | LMNA (0.46) | ALDH1A3LMNATYRALDH1A1ALDH3A1 | |
| SCHEMBL10736418 | 0.82 | CYP2A6 (0.59) | ALDH1A3LMNATYRALDH1A1ALDH3A1 | |
| Ethylene SCHEMBL10689209 | 0.82 | ALDH1A1 (0.40) | ALDH1A3LMNATYRALDH1A1ALDH3A1 | |
| Benzaldehyde SCHEMBL19924275 | 0.81 | ALDH1A1 (0.47) | ALDH1A3LMNATYRALDH1A1ALDH3A1 | |
| Ethylene SCHEMBL9411096 | 0.81 | ALDH1A1 (0.44) | ALDH1A3LMNATYRALDH1A1ALDH3A1 | |
| Ethylene SCHEMBL9726739 | 0.81 | ALDH1A3 (0.38) | ALDH1A3LMNATYRALDH1A1ALDH3A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1216522-A | Therapeutic agent for diabetes | JAPAN TOBACCO INC (JP) | 1999-05-12 | — | — | CN | disclosed |
| EP-0885869-A1 | THERAPEUTIC AGENT FOR DIABETES | Japan Tobacco Inc. (JP) | 1998-12-23 | — | — | EP | disclosed |