Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1B | P00325 | 4/20 | 0.40 |
| ▸ | ADH1A | P07327 | 4/20 | 0.40 |
| ▸ | ADH7 | P40394 | 3/20 | 0.40 |
| ▸ | ADH1C | P00326 | 3/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | ADH4 | P08319 | 1/20 | 0.36 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.33 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.32 |
| ▸ | GGT1 | P19440 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3664299 | 0.81 | TET2 (0.44) | ADH1BADH1AADH7ADH1CEPHX1 | |
| SCHEMBL27839470 | 0.81 | TET2 (0.44) | ADH1BADH1AADH7ADH1CEPHX1 | |
| SCHEMBL28144230 | 0.79 | GSR (0.46) | GGT1 | |
| SCHEMBL17017527 | 0.79 | GABRR1 (0.52) | ADH1BADH1AADH7ADH1CEPHX1 | |
| SCHEMBL14882799 | 0.76 | SLC1A3 (0.39) | ADH1BADH1AADH7ADH1CEPHX1 | |
| SCHEMBL7489908 | 0.74 | HDAC1 (0.61) | ADH1BADH1AADH7ADH1CEPHX1 | |
| SCHEMBL15903900 | 0.74 | ADH1B (0.37) | ADH1BADH1AADH7ADH1CEPHX1 | |
| SCHEMBL8535256 | 0.74 | ADH1B (0.41) | ADH1BADH1AADH7ADH1CEPHX1 | |
| SCHEMBL3598306 | 0.74 | — | — | |
| SCHEMBL23099385 | 0.72 | LTA4H (0.47) | ADH1BADH1AADH7ADH1CEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5763437-A | Benzodiazepine derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-06-09 | — | — | US | claimed |
| EP-0804425-A2 | BENZODIAZEPINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-11-05 | — | — | EP | claimed |
| WO-1996004254-A2 | BENZODIAZEPINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-02-15 | — | — | WO | claimed |
| US-5763437-A | Benzodiazepine derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-06-09 | — | — | US | disclosed |
| WO-1996004254-A2 | BENZODIAZEPINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-02-15 | — | — | WO | disclosed |