Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 20/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8630088 | 1.00 | CCR5 (0.40) | CCR5 | |
| SCHEMBL8541841 | 0.89 | CCR5 (0.35) | CCR5 | |
| SCHEMBL8541612 | 0.88 | ALDH1A1 (0.39) | CCR5 | |
| SCHEMBL8437869 | 0.87 | CCR5 (0.38) | CCR5 | |
| SCHEMBL8440492 | 0.87 | CCR5 (0.38) | CCR5 | |
| SCHEMBL8447213 | 0.87 | GRIN2B (0.37) | CCR5 | |
| SCHEMBL7450103 | 0.87 | GRIN2B (0.37) | CCR5 | |
| SCHEMBL8602692 | 0.87 | ALDH1A1 (0.39) | CCR5 | |
| SCHEMBL8435146 | 0.87 | ALDH1A1 (0.39) | CCR5 | |
| SCHEMBL7452820 | 0.86 | CCR5 (0.34) | CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0518558-B1 | 1-Methylcarbapenem derivatives, their preparation and their use as antibiotics | SANKYO CO (JP) | 1998-09-02 | — | — | EP | disclosed |
| EP-0518558-A1 | 1-Methylcarbapenem derivatives, their preparation and their use as antibiotics | Sankyo Company Limited (JP) | 1992-12-16 | — | — | EP | disclosed |