Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CCR5 | P51681 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8602692 | 1.00 | ALDH1A1 (0.39) | ALDH1A1MAPTHPGDTDP1CCR5 | |
| SCHEMBL8536719 | 0.87 | CCR5 (0.40) | CCR5 | |
| SCHEMBL8630088 | 0.87 | CCR5 (0.40) | CCR5 | |
| SCHEMBL8521252 | 0.86 | MAPT (0.39) | ALDH1A1MAPTHPGDTDP1ATM | |
| SCHEMBL8521254 | 0.86 | MAPT (0.39) | ALDH1A1MAPTHPGDTDP1ATM | |
| SCHEMBL8521258 | 0.86 | MAPT (0.39) | ALDH1A1MAPTHPGDTDP1ATM | |
| SCHEMBL9728223 | 0.86 | DPP8 (0.46) | TDP1 | |
| SCHEMBL9199817 | 0.86 | TDP1 (0.40) | ALDH1A1MAPTHPGDTDP1ATM | |
| Trifluoromethanesulfonic Acid SCHEMBL8537596 | 0.86 | CCR5 (0.39) | ALDH1A1CCR5 | |
| Trifluoromethanesulfonic Acid SCHEMBL9574325 | 0.86 | CCR5 (0.39) | ALDH1A1CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5866564-A | STABILITY | SANKYO COMPANY, LIMITED (JP) | 1999-02-02 | — | — | US | disclosed |
| US-5712267-A | Carbapenem derivatives, their preparation and their use as antibiotics | SANKYO COMPANY,. LIMITED (JP) | 1998-01-27 | — | — | US | disclosed |
| EP-0560613-A1 | Antimicrobial carbapenem derivatives, their preparation and their therapeutic use | SANKYO COMPANY LIMITED (JP) | 1993-09-15 | — | — | EP | disclosed |