Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | PTGES | O14684 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 6/20 | 0.43 |
| ▸ | ITGAV | P06756 | 6/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | PARP1 | P09874 | 2/20 | 0.43 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.43 |
| ▸ | PARP14 | Q460N5 | 2/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.43 |
| ▸ | PLAU | P00749 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7501198 | 0.84 | PKM (0.48) | PKMPTGESNPC1RAB9ACYP3A4 | |
| SCHEMBL8441146 | 0.83 | PKM (0.48) | PKMPTGESITGB3ITGAVITGA2B | |
| SCHEMBL9302930 | 0.80 | PTGES (0.51) | PTGESNPC1RAB9ACYP3A4CYP1A2 | |
| SCHEMBL7497491 | 0.78 | ITGB3 (0.68) | PKMNPC1RAB9AITGB3ITGAV | |
| SCHEMBL7497495 | 0.78 | ITGB3 (0.68) | PKMNPC1RAB9AITGB3ITGAV | |
| SCHEMBL7500870 | 0.78 | ITGB3 (0.68) | PKMITGB3ITGAVITGA2BKMT2A | |
| SCHEMBL7502133 | 0.78 | ITGB3 (0.68) | PKMITGB3ITGAVITGA2BMAPT | |
| SCHEMBL7499768 | 0.78 | ITGB3 (0.68) | PKMITGB3ITGAVITGA2BPARP1 | |
| SCHEMBL7502905 | 0.78 | ITGB3 (0.68) | PKMITGB3ITGAVITGA2BMAPT | |
| SCHEMBL7507092 | 0.78 | ITGB3 (0.68) | PKMITGB3ITGAVITGA2BKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852210-A | Cinnamic acid derivatives | G. D. SEARLE & CO. (US) | 1998-12-22 | — | — | US | claimed |