Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | PTGES | O14684 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27382709 | 0.85 | HPGD (0.48) | HPGDKMT2AALDH1A1L3MBTL1MAPT | |
| SCHEMBL9452058 | 0.81 | KMT2A (0.39) | HPGDKMT2AALDH1A1L3MBTL1NPSR1 | |
| SCHEMBL11630352 | 0.79 | KMT2A (0.59) | HPGDKMT2AALDH1A1MAPTALOX15 | |
| SCHEMBL4748576 | 0.79 | KMT2A (0.44) | HPGDKMT2AALDH1A1MAPTNPSR1 | |
| SCHEMBL1820379 | 0.77 | MEN1 (0.47) | HPGDKMT2AALDH1A1MAPTNPSR1 | |
| SCHEMBL28392912 | 0.75 | MEN1 (0.51) | HPGDKMT2AALDH1A1MAPTALOX15 | |
| SCHEMBL28401782 | 0.73 | L3MBTL1 (0.46) | HPGDKMT2AALDH1A1L3MBTL1MAPT | |
| SCHEMBL5696331 | 0.72 | L3MBTL1 (0.49) | HPGDKMT2AALDH1A1L3MBTL1MAPT | |
| SCHEMBL3276086 | 0.72 | L3MBTL1 (0.61) | HPGDKMT2AALDH1A1L3MBTL1MAPT | |
| SCHEMBL11584097 | 0.71 | LMNA (0.47) | HPGDKMT2AALDH1A1L3MBTL1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5726195-A | Aminoacyl adenylate mimics as novel antimicrobial and antiparasitic agents | CUBIST PHARMACEUTICALS, INC. (US) | 1998-03-10 | — | — | US | disclosed |
| WO-1997005132-A1 | AMINOACYL ADENYLATE MIMICS AS NOVEL ANTIMICROBIAL AND ANTIPARASITIC AGENTS | CUBIST PHARMACEUTICALS, INC. (US) | 1997-02-13 | — | — | WO | disclosed |