Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 2/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.38 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.38 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.38 |
| ▸ | CCND1 | P24385 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11630352 | 0.83 | KMT2A (0.59) | KMT2AALDH1A1SMN1; SMN2NPSR1LMNA | |
| SCHEMBL3045678 | 0.80 | KMT2A (0.46) | KMT2AALDH1A1SMN1; SMN2NPSR1LMNA | |
| SCHEMBL28392912 | 0.79 | MEN1 (0.51) | KMT2AALDH1A1SMN1; SMN2NPSR1TP53 | |
| SCHEMBL8536886 | 0.79 | HPGD (0.42) | KMT2AALDH1A1SMN1; SMN2NPSR1LMNA | |
| SCHEMBL11492117 | 0.78 | CA2 (0.45) | KMT2AALDH1A1SMN1; SMN2NPSR1LMNA | |
| SCHEMBL9452058 | 0.75 | KMT2A (0.39) | KMT2AALDH1A1SMN1; SMN2NPSR1LMNA | |
| SCHEMBL3831587 | 0.74 | ALDH1A1 (0.47) | KMT2AALDH1A1SMN1; SMN2NPSR1LMNA | |
| SCHEMBL2033767 | 0.74 | KMT2A (0.41) | KMT2AALDH1A1SMN1; SMN2NPSR1LMNA | |
| SCHEMBL7086352 | 0.74 | HNF4A (0.40) | KMT2AALDH1A1SMN1; SMN2NPSR1LMNA | |
| SCHEMBL5624141 | 0.74 | MEN1 (0.39) | KMT2AALDH1A1SMN1; SMN2HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008109991-A1 | INHIBITORS OF CARNITINE PALMITOYLTRANSFERASE AND TREATING CANCER | UNIVERSITY HEALTH NETWORK (CA) | 2008-09-18 | — | — | WO | disclosed |