Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11376813 | 0.84 | MGAM (0.39) | TSHRKMT2AALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL8533430 | 0.78 | ALDH1A1 (0.43) | LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL8536096 | 0.78 | LMNA (0.39) | TSHRLMNAKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL12676103 | 0.75 | ALDH1A1 (0.37) | LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL14865334 | 0.74 | TSHR (0.46) | TSHRLMNAKDM4EKMT2AALDH1A1 | |
| SCHEMBL3239419 | 0.73 | ALDH1A1 (0.38) | TSHRLMNAALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL19383627 | 0.73 | ALDH1A1 (0.38) | TSHRLMNAALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL3531364 | 0.73 | MGAM (0.44) | TSHRLMNAKDM4EKMT2AALDH1A1 | |
| SCHEMBL5505303 | 0.72 | TSHR (0.48) | TSHRLMNAKDM4EKMT2AALDH1A1 | |
| SCHEMBL5799860 | 0.72 | TSHR (0.50) | TSHRLMNAKMT2AALDH1A1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1216522-A | Therapeutic agent for diabetes | JAPAN TOBACCO INC (JP) | 1999-05-12 | — | — | CN | disclosed |
| EP-0885869-A1 | THERAPEUTIC AGENT FOR DIABETES | Japan Tobacco Inc. (JP) | 1998-12-23 | — | — | EP | disclosed |