Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.37 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | CETP | P11597 | 2/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8536096 | 0.83 | LMNA (0.39) | ALDH1A1SMN1; SMN2LMNASLC15A2FFAR3 | |
| SCHEMBL12676103 | 0.80 | ALDH1A1 (0.37) | ALDH1A1SMN1; SMN2LMNAFFAR3HSD11B1 | |
| SCHEMBL8537221 | 0.78 | TSHR (0.50) | ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL22175253 | 0.77 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2FFAR3CETPP2RX7 | |
| SCHEMBL12883183 | 0.75 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2LMNAFFAR3HSD11B1 | |
| SCHEMBL22550126 | 0.75 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2LMNAFFAR3HSD11B1 | |
| SCHEMBL7080167 | 0.75 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2LMNAFFAR3HSD11B1 | |
| SCHEMBL7080172 | 0.75 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2LMNAFFAR3HSD11B1 | |
| SCHEMBL3239419 | 0.73 | ALDH1A1 (0.38) | ALDH1A1SMN1; SMN2LMNAFFAR3HSD11B1 | |
| SCHEMBL21238456 | 0.73 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2LMNAFFAR3HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885869-A1 | THERAPEUTIC AGENT FOR DIABETES | Japan Tobacco Inc. (JP) | 1998-12-23 | — | — | EP | disclosed |