Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 16/20 | 0.48 |
| ▸ | CYP11B1 | P15538 | 14/20 | 0.48 |
| ▸ | EGLN2 | Q96KS0 | 3/20 | 0.46 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8538740 | 0.83 | NISCH (0.46) | NISCH | |
| SCHEMBL3978330 | 0.81 | NISCH (0.45) | NISCH | |
| SCHEMBL1288737 | 0.80 | NISCH (0.53) | CYP11B2CYP11B1NISCH | |
| SCHEMBL7425938 | 0.78 | NISCH (0.45) | NISCH | |
| SCHEMBL28829248 | 0.76 | NISCH (0.49) | CYP11B2CYP11B1NISCH | |
| SCHEMBL7060159 | 0.76 | NISCH (0.49) | NISCH | |
| SCHEMBL18297999 | 0.75 | CYP11B2 (0.67) | CYP11B2CYP11B1 | |
| SCHEMBL5012098 | 0.75 | PDE4A (0.44) | NISCH | |
| SCHEMBL9514239 | 0.73 | CYP11B2 (0.54) | CYP11B2CYP11B1EGLN2 | |
| SCHEMBL31605617 | 0.73 | CYP11B2 (0.54) | CYP11B2CYP11B1EGLN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0857171-A2 | IMIDAZOLE DERIVATIVES AND THE USE THEREOF AS NITROGEN MONOXIDE SYNTHASE INHIBITORS | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-08-12 | — | — | EP | disclosed |
| WO-1997015555-A2 | IMIDAZOLE DERIVATIVES AND THE USE THEREOF AS NITROGEN MONOXIDE SYNTHASE INHIBITORS | SCHERING AKTIENGESELLSCHAFT (DE) | 1997-05-01 | — | — | WO | disclosed |