Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.69 |
| ▸ | TSHR | P16473 | 2/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.66 |
| ▸ | NPC1 | O15118 | 3/20 | 0.66 |
| ▸ | RAB9A | P51151 | 3/20 | 0.66 |
| ▸ | LMNA | P02545 | 3/20 | 0.65 |
| ▸ | TP53 | P04637 | 1/20 | 0.65 |
| ▸ | CASP3 | P42574 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.65 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.65 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.65 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.65 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.48 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.47 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methabenzthiazuron SCHEMBL66434 | 1.00 | ALOX15 (0.69) | ALOX15TSHRALDH1A1NPC1RAB9A | |
| Methabenzthiazuron SCHEMBL29549492 | 1.00 | ALOX15 (0.69) | ALOX15TSHRALDH1A1NPC1RAB9A | |
| Methabenzthiazuron SCHEMBL7109380 | 0.97 | ALOX15 (0.66) | ALOX15TSHRALDH1A1NPC1RAB9A | |
| Methabenzthiazuron SCHEMBL19893745 | 0.97 | ALOX15 (0.66) | ALOX15TSHRALDH1A1NPC1RAB9A | |
| Methabenzthiazuron SCHEMBL28163689 | 0.97 | ALOX15 (0.66) | ALOX15TSHRALDH1A1NPC1RAB9A | |
| Methabenzthiazuron SCHEMBL11351797 | 0.94 | ALOX15 (0.63) | ALOX15TSHRALDH1A1NPC1RAB9A | |
| Methabenzthiazuron SCHEMBL9451072 | 0.92 | ALOX15 (0.60) | ALOX15TSHRALDH1A1NPC1RAB9A | |
| Methabenzthiazuron SCHEMBL11351792 | 0.92 | ALOX15 (0.60) | ALOX15TSHRALDH1A1NPC1RAB9A | |
| Methabenzthiazuron SCHEMBL27354229 | 0.92 | ALDH1A1 (0.61) | ALOX15TSHRALDH1A1NPC1RAB9A | |
| Methabenzthiazuron SCHEMBL17260861 | 0.87 | CYP3A4 (0.68) | ALOX15TSHRALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0574418-B1 | ARYL SULPHONYL UREA COMPOUNDS, A METHOD OF PREPARING THEM, AND THEIR USE AS HERBICIDES AND GROWTH REGULATORS | HOECHST SCHERING AGREVO GMBH (DE) | 1998-11-11 | — | — | EP | disclosed |
| US-5688745-A | Arylsulfonylureas and their use as herbicides and growth regulators | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-11-18 | — | — | US | disclosed |
| US-5463081-A | Chemical intermediates | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-10-31 | — | — | US | disclosed |
| CN-1064387-A | The weed killer herbicide of citrus, sugarcane, oil palm etc. | DU PONT (US) | 1992-09-16 | — | — | CN | disclosed |
| CN-1064077-A | Bicyclic ethers with weeding activity | DU PONT (US) | 1992-09-02 | — | — | CN | disclosed |
| WO-1992013845-A1 | ARYL SULPHONYL UREA COMPOUNDS, A METHOD OF PREPARING THEM, AND THEIR USE AS HERBICIDES AND GROWTH REGULATORS | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-08-20 | — | — | WO | disclosed |
| CN-1047287-A | The alkanoylpyridinesulfonylureas of weeding | DU PONT (US) | 1990-11-28 | — | — | CN | disclosed |
| CN-1038281-A | HERBICIDAL OXABICYCLOALKAWE ETHERS | DU PONT (US) | 1989-12-27 | — | — | CN | disclosed |
| US-4424073-A | N-(PYRIMIDINYLAMINOCARBONYL/SULFONAMIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-01-03 | — | — | US | disclosed |