⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17974196 | 0.78 | KDM4E (0.45) | — | |
| SCHEMBL29144661 | 0.78 | LMNA (0.45) | — | |
| SCHEMBL24694384 | 0.77 | TDP1 (0.39) | — | |
| SCHEMBL10884018 | 0.77 | ALDH1A1 (0.32) | — | |
| SCHEMBL3102816 | 0.76 | — | — | |
| SCHEMBL17265366 | 0.76 | — | — | |
| SCHEMBL18900660 | 0.74 | TDP1 (0.36) | — | |
| SCHEMBL8472632 | 0.73 | — | — | |
| SCHEMBL6308650 | 0.73 | — | — | |
| SCHEMBL1122114 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5834407-A | ANTIWEAR AND EXTREME PRESSURE OIL ADDITIVE COMPRISING HYDROCARBYL SUBSTITUTED-2-(THIO OR OXO)-1,3-DITHIOLANE, OXATHIOLANE OR THIAZOLIDINES AS SUBSTITUTE FOR ZINC DIALKYL DITHIOPHOSPHATE | THE LUBRIZOL CORPORATION (US) | 1998-11-10 | — | — | US | disclosed |
| EP-0825246-A2 | Lubricants and functional fluids containing heterocyclic compounds | The Lubrizol Corporation (US) | 1998-02-25 | — | — | EP | disclosed |
| EP-0825247-A2 | Compositions containing thiocarbonates and acylated-nitrogen containing compounds | The Lubrizol Corporation (US) | 1998-02-25 | — | — | EP | disclosed |
| EP-0326586-B1 | PHOSPHITE ESTER COMPOSITIONS, AND LUBRICANTS AND FUNCTIONAL FLUIDS CONTAINING SAME | The Lubrizol Corporation (US) | 1993-03-17 | — | — | EP | disclosed |
| US-4752416-A | MIXTURE WITH SULFUR CONTAINING COMPOUNDS | THE LUBRIZOL CORPORATION (US) | 1988-06-21 | — | — | US | disclosed |
| US-4031023-A | Lubricating compositions and methods utilizing hydroxy thioethers | THE LUBRIZOL CORPORATION (US) | 1977-06-21 | — | — | US | disclosed |