Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTPA | P49638 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Carbromal SCHEMBL8931164 | 0.81 | — | — | |
| SCHEMBL8867454 | 0.81 | CYP3A4 (0.31) | KMT2ACYP1A2 | |
| SCHEMBL8532916 | 0.81 | CYP3A4 (0.31) | KMT2ACYP1A2 | |
| Hydrochloric Acid SCHEMBL8931170 | 0.80 | GMNN (0.32) | KMT2A | |
| Water SCHEMBL8931171 | 0.80 | USP2 (0.30) | KMT2A | |
| SCHEMBL8534827 | 0.80 | TTPA (0.39) | TTPAMEN1KMT2APDE4APDE3A | |
| Hydrochloric Acid SCHEMBL8867577 | 0.79 | GMNN (0.31) | KMT2A | |
| Hydrochloric Acid SCHEMBL8867573 | 0.79 | GMNN (0.31) | KMT2A | |
| SCHEMBL8537258 | 0.75 | MEN1 (0.37) | TTPAMEN1KMT2ACYP1A2 | |
| Carbromal SCHEMBL8931168 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5721233-A | Derivatives of 2,3-dihydro benzofuranols | MERRELL PHARMACEUTICALS INC. (US) | 1998-02-24 | — | — | US | claimed |
| EP-0635009-B1 | NOVEL DERIVATIVES OF 2,3-DIHYDRO-2,2,4,6,7-PENTAALKYL-5-BENZOFURANOLS | MERRELL PHARMA INC (US) | 1997-09-17 | — | — | EP | claimed |