Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTPA | P49638 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8537446 | 0.80 | TTPA (0.36) | TTPAMEN1KMT2APDE4APDE3A | |
| SCHEMBL8537504 | 0.79 | TTPA (0.37) | TTPAMEN1KMT2APDE4APDE3A | |
| SCHEMBL9285775 | 0.78 | TTPA (0.36) | TTPAMEN1KMT2APDE4APDE3A | |
| SCHEMBL10473129 | 0.77 | TTPA (0.38) | TTPAMEN1KMT2APDE4APDE3A | |
| SCHEMBL8537258 | 0.77 | MEN1 (0.37) | TTPAMEN1KMT2A | |
| SCHEMBL8931169 | 0.77 | TTPA (0.36) | TTPAMEN1KMT2APDE4APDE3A | |
| SCHEMBL8534407 | 0.76 | ALOX5 (0.33) | ALOX5 | |
| SCHEMBL9665291 | 0.72 | TTPA (0.33) | TTPAMEN1KMT2APDE4APDE3A | |
| SCHEMBL9088900 | 0.71 | TTPA (0.36) | TTPAMEN1KMT2APDE4APDE3A | |
| SCHEMBL9087758 | 0.71 | TTPA (0.36) | TTPAMEN1KMT2APDE4APDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5721233-A | Derivatives of 2,3-dihydro benzofuranols | MERRELL PHARMACEUTICALS INC. (US) | 1998-02-24 | — | — | US | disclosed |
| EP-0635009-B1 | NOVEL DERIVATIVES OF 2,3-DIHYDRO-2,2,4,6,7-PENTAALKYL-5-BENZOFURANOLS | MERRELL PHARMA INC (US) | 1997-09-17 | — | — | EP | disclosed |
| EP-0635009-A1 | NOVEL DERIVATIVES OF 2,3-DIHYDRO-2,2,4,6,7-PENTAALKYL-5-BENZOFURANOLS. | MERRELL DOW PHARMA (US) | 1995-01-25 | — | — | EP | disclosed |
| WO-1993020057-A1 | NOVEL DERIVATIVES OF 2,3-DIHYDRO-2,2,4,6,7-PENTAALKYL-5-BENZOFURANOLS | MERRELL DOW PHARMACEUTICALS INC. (US) | 1993-10-14 | — | — | WO | disclosed |