Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.34 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TTPA | P49638 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL8537257 | 0.84 | MEN1 (0.38) | MEN1KMT2AALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL8534827 | 0.77 | TTPA (0.39) | MEN1KMT2ATTPA | |
| SCHEMBL8537446 | 0.75 | TTPA (0.36) | MEN1KMT2ACYP1A2TTPA | |
| SCHEMBL8537504 | 0.68 | TTPA (0.37) | MEN1KMT2ATTPA | |
| SCHEMBL9285775 | 0.67 | TTPA (0.36) | MEN1KMT2ATTPA | |
| SCHEMBL9665291 | 0.67 | TTPA (0.33) | MEN1KMT2ATTPA | |
| SCHEMBL8931169 | 0.66 | TTPA (0.36) | MEN1KMT2ATTPA | |
| SCHEMBL10473129 | 0.64 | TTPA (0.38) | MEN1KMT2ATTPA | |
| SCHEMBL8867575 | 0.63 | KCNE1 (0.38) | MAPTALDH1A1HPGDGAAHSD17B10 | |
| SCHEMBL8868743 | 0.63 | KCNE1 (0.38) | MAPTALDH1A1HPGDGAAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5721233-A | Derivatives of 2,3-dihydro benzofuranols | MERRELL PHARMACEUTICALS INC. (US) | 1998-02-24 | — | — | US | disclosed |
| EP-0635009-B1 | NOVEL DERIVATIVES OF 2,3-DIHYDRO-2,2,4,6,7-PENTAALKYL-5-BENZOFURANOLS | MERRELL PHARMA INC (US) | 1997-09-17 | — | — | EP | disclosed |
| EP-0635009-A1 | NOVEL DERIVATIVES OF 2,3-DIHYDRO-2,2,4,6,7-PENTAALKYL-5-BENZOFURANOLS. | MERRELL DOW PHARMA (US) | 1995-01-25 | — | — | EP | disclosed |
| WO-1993020057-A1 | NOVEL DERIVATIVES OF 2,3-DIHYDRO-2,2,4,6,7-PENTAALKYL-5-BENZOFURANOLS | MERRELL DOW PHARMACEUTICALS INC. (US) | 1993-10-14 | — | — | WO | disclosed |