SCHEMBL8537529

SCHEMBL8537529

CC(=O)Nc1ccc(C)c(O)c1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.62
PKM P14618 1/20 0.61
KMT2A Q03164 5/20 0.60
MEN1 O00255 4/20 0.60
CYP1A2 P05177 3/20 0.60
CYP2D6 P10635 2/20 0.60
CYP2C9 P11712 2/20 0.60
CYP2C19 P33261 2/20 0.60
CYP3A4 P08684 2/20 0.60
GAA P10253 1/20 0.60
SMN1; SMN2 Q16637 3/20 0.59
POLB P06746 1/20 0.57
MAPT P10636 2/20 0.55
TDP1 Q9NUW8 1/20 0.55
CA12 O43570 1/20 0.55
BRD4 O60885 1/20 0.55
NR1I2 O75469 1/20 0.55
CA1 P00915 1/20 0.55
CA2 P00918 1/20 0.55
MB P02144 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2853227 0.86 ALDH1A1 (0.64) ALDH1A1PKMKMT2AMEN1CYP1A2
SCHEMBL7547627 0.84 ALDH1A1 (0.59) ALDH1A1PKMKMT2AMEN1CYP1A2
SCHEMBL2336203 0.83 POLB (0.68) ALDH1A1PKMKMT2AMEN1CYP1A2
SCHEMBL3192352 0.83 PKM (0.65) ALDH1A1PKMKMT2AMEN1CYP1A2
SCHEMBL29990241 0.83 POLB (0.68) ALDH1A1PKMKMT2AMEN1CYP1A2
SCHEMBL3047568 0.82 ALDH1A1 (0.60) ALDH1A1KMT2AMEN1CYP1A2CYP2D6
SCHEMBL7093312 0.81 ALDH1A1 (0.58) ALDH1A1KMT2AMEN1CYP1A2CYP2D6
SCHEMBL11518967 0.81 ALDH1A1 (0.58) ALDH1A1KMT2AMEN1CYP1A2CYP2D6
SCHEMBL4958020 0.80 MAPT (0.69) ALDH1A1PKMKMT2AMEN1CYP1A2
SCHEMBL8716883 0.80 KMT2A (0.65) ALDH1A1PKMKMT2AMEN1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4985042-A New substituted metaaminophenols, a process for their preparation, hair-dyeing compositions containing them and a hair-dyeing process L'OREAL (FR) 1991-01-15 US claimed
US-4954131-A Substituted metaaminophenols, a process for their preparation, hair-dyeing compositions containing them and a hair-dyeing process L'OREAL (FR) 1990-09-04 US claimed
US-4863480-A OXIDATION COLOR DYES THE FRENCH JOINT STOCK COMPANY "L'OREAL" (FR) 1989-09-05 US claimed
US-4563188-A SHADES OF GREEN L'OREAL (FR) 1986-01-07 US claimed
US-4337061-A NITRO DYES IN AQUEOUS SOLUTION SOCIETE ANONYME DITE: L'OREAL (FR) 1982-06-29 US claimed
US-4200432-A HAIR DYES L'OREAL (FR) 1980-04-29 US claimed
US-4094635-A Meta-aminophenol sulfonamides as couplers in hair dye compositions L'OREAL (FR) 1978-06-13 US claimed
US-3961879-A P-PHENYLENEDIAMINE, HAIR L'OREAL (FR) 1976-06-08 US claimed
US-3948596-A Oxidation dye for keratinic fibers containing 2-halo-5-acetaminophenol as a coupler SOCIETE ANONYME DITE: L'OREAL (FR) 1976-04-06 US claimed
WO-2022191865-A1 HAIR COLORANT ASSESSMENT, SELECTION AND FORMULATION SYSTEM Innovative Beauty LLC (US) 2022-09-15 WO disclosed
US-20220283032-A1 Hair Colorant Assessment, Selection And Formulation System Innovative Beauty LLC (US) 2022-09-08 US disclosed
US-11378457-B1 Hair colorant assessment, selection and formulation system Innovative Beauty LLC (US) 2022-07-05 US disclosed
US-11137291-B1 Hair colorant assessment, selection and formulation system Innovative Beauty LLC (US) 2021-10-05 US disclosed
EP-0630642-B1 Naphthol couplers BRISTOL MYERS SQUIBB CO (US) 1998-08-12 EP disclosed
US-3977825-A Indoanilines in keratinic fiber dye cmpositions L'OREAL (FR) 1976-08-31 US disclosed
US-3978040-A Process for the preparation of cyanoazo compounds by reacting halogenoazo compounds with CuCN in an aqueous media in the presence of a nitrogen base BAYER AKTIENGESELLSCHAFT (DT) 1976-08-31 US disclosed
US-3961879-A P-PHENYLENEDIAMINE, HAIR L'OREAL (FR) 1976-06-08 US disclosed
US-3955918-A Azo derivatives or pyridine N-oxide for use in hair dye compositions SOCIETE ANONYME DITE: L'OREAL (FR) 1976-05-11 US disclosed
US-3953508-A Diphenylamines for dyeing keratinous fibers L'OREAL (FR) 1976-04-27 US disclosed
US-3948596-A Oxidation dye for keratinic fibers containing 2-halo-5-acetaminophenol as a coupler SOCIETE ANONYME DITE: L'OREAL (FR) 1976-04-06 US disclosed