SCHEMBL4958020

SCHEMBL4958020

CC(=O)Nc1ccc(NC(C)=O)c(O)c1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.69
POLB P06746 2/20 0.69
NPC1 O15118 2/20 0.69
RAB9A P51151 2/20 0.69
PKM P14618 1/20 0.61
SMN1; SMN2 Q16637 2/20 0.59
ALDH1A1 P00352 2/20 0.55
MEN1 O00255 2/20 0.55
KMT2A Q03164 2/20 0.55
CA12 O43570 1/20 0.55
BRD4 O60885 1/20 0.55
NR1I2 O75469 1/20 0.55
CA1 P00915 1/20 0.55
CA2 P00918 1/20 0.55
MB P02144 1/20 0.55
CYP1A1 P04798 1/20 0.55
CA3 P07451 1/20 0.55
CYP3A4 P08684 1/20 0.55
RARG P13631 1/20 0.55
TSHR P16473 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9524929 0.89 HTT (0.59) MAPTPOLBNPC1RAB9APKM
Hydrochloric Acid SCHEMBL9627355 0.87 HTT (0.58) MAPTPOLBNPC1RAB9APKM
SCHEMBL9095112 0.86 POLB (0.57) MAPTPOLBNPC1RAB9APKM
SCHEMBL6941725 0.85 RAB9A (0.51) MAPTPOLBNPC1RAB9APKM
SCHEMBL11417747 0.84 SMN1; SMN2 (0.59) MAPTPOLBNPC1RAB9APKM
SCHEMBL3192352 0.83 PKM (0.65) MAPTPOLBNPC1RAB9APKM
SCHEMBL6807072 0.83 PKM (0.51) MAPTPOLBNPC1RAB9APKM
SCHEMBL3715569 0.82 POLB (0.67) MAPTPOLBNPC1RAB9APKM
SCHEMBL14209030 0.82 POLB (0.60) MAPTPOLBNPC1RAB9ASMN1; SMN2
SCHEMBL11639262 0.82 ALDH1A1 (0.58) MAPTNPC1RAB9APKMSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015013456-A1 INDICATOR COMPOUNDS, POLYMERIZABLE DERIVATIVES THEREOF AND INFECTION INDICATING MEDICAL DEVICES COMPRISING THE SAME INDICATOR SYSTEMS INTERNATIONAL, INC. (US) 2015-01-29 WO disclosed
EP-1871844-B1 BUBBLE COMPOSITION WITH COLOR CHANGING INDICATOR C2C TECHNOLOGIES LLC (US) 2014-08-27 EP disclosed
EP-1529816-B1 Azo dye FUJIFILM CORP (JP) 2011-01-05 EP disclosed
US-7358344-B2 Stable, nondegrading; pollution control FUJIFILM CORPORATION (JP) 2008-04-15 US disclosed
US-7358344-B2 Stable, nondegrading; pollution control FUJIFILM CORPORATION (JP) 2008-04-15 US disclosed
EP-1871844-A2 NOVELTY COMPOSITIONS WITH COLOR CHANGING INDICATOR C2C Technologies LLC (US) 2008-01-02 EP disclosed
WO-2007008389-A2 USE OF COLOR CHANGING INDICATORS IN CONSUMER PRODUCTS C2C TECHNOLOGIES LLC (US) 2007-01-18 WO disclosed
US-20070010400-A1 Use of color changing indicators in consumer products C2C TECHNOLOGIES, LLC 2007-01-11 US disclosed
US-20060257439-A1 Cleansing compositions with color changing indicator CRAYOLA LLC 2006-11-16 US disclosed
US-20060236470-A1 Novelty compositions with color changing indicator CRAYOLA LLC 2006-10-26 US disclosed
WO-2006105193-A2 PERSONAL CARE COMPOSITIONS WITH COLOR CHANGING INDICATOR C2C TECHNOLOGIES LLC (US) 2006-10-05 WO disclosed
WO-2006105260-A1 ORAL CARE COMPOSITIONS WITH COLOR CHANGING INDICATOR C2C TECHNOLOGIES LLC (US) 2006-10-05 WO disclosed
WO-2006105261-A1 CLEANSING COMPOSITIONS WITH COLOR CHANGING INDICATOR C2C TECHNOLOGIES LLC (US) 2006-10-05 WO disclosed
WO-2006105191-A2 NOVELTY COMPOSITIONS WITH COLOR CHANGING INDICATOR C2C TECHNOLOGIES LLC (US) 2006-10-05 WO disclosed
US-20060222601-A1 Oral care compositions with color changing indicator C2C TECHNOLOGIES, LLC 2006-10-05 US disclosed
US-20060222675-A1 Personal care compositions with color changing indicator C2C TECHNOLOGIES, LLC 2006-10-05 US disclosed
US-5372917-A Excellent color forming property, storage stability and recorded image preservability; pyrazolone derivatives KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1994-12-13 US disclosed
US-RE34737-E Dye transfer sheet for sublimation heat-sensitive transfer recording MITSUBISHI KASEI CORPORATION (JP) 1994-09-20 US disclosed
US-4829047-A INDOPHENOL DYES, STORAGE STABILITY MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) 1989-05-09 US disclosed
US-3953508-A Diphenylamines for dyeing keratinous fibers L'OREAL (FR) 1976-04-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060222675-A1 Personal care compositions with color changing indicator CUTA, POLR1C, TYR MAPT 2485/4885POLB 157/4885NPC1 4491/4885
US-20060257439-A1 Cleansing compositions with color changing indicator WASHC5, WASHC4, FHIT MAPT 3034/4885POLB 867/4885NPC1 3586/4885
US-20060222601-A1 Oral care compositions with color changing indicator CA9, CA7, TAS2R7 MAPT 3664/4885POLB 434/4885NPC1 2933/4885
US-20070010400-A1 Use of color changing indicators in consumer products NQO2, CA4, CA7 MAPT 3518/4885POLB 2689/4885NPC1 4141/4885
US-20060236470-A1 Novelty compositions with color changing indicator MITF, CRABP2, SHH MAPT 720/4885POLB 470/4885NPC1 1265/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.