Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 1/20 | 0.39 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CCKBR | P32239 | 9/20 | 0.38 |
| ▸ | CCKAR | P32238 | 7/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | AKT1 | P31749 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8773977 | 1.00 | PRMT5 (0.39) | PRMT5WDR77ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL8775246 | 0.87 | CCKBR (0.41) | CCKBRCCKAR | |
| SCHEMBL8537754 | 0.87 | CCKBR (0.41) | CCKBRCCKAR | |
| SCHEMBL8535409 | 0.86 | CCKBR (0.42) | CCKBRCCKAR | |
| SCHEMBL8535401 | 0.86 | CCKBR (0.42) | CCKBRCCKAR | |
| SCHEMBL8537391 | 0.84 | CCKBR (0.43) | CCKBRCCKAR | |
| SCHEMBL8537384 | 0.84 | CCKBR (0.43) | CCKBRCCKAR | |
| SCHEMBL9573650 | 0.82 | ALDH1A1 (0.52) | ALDH1A1CCKBRCCKAR | |
| SCHEMBL8773986 | 0.82 | CCKBR (0.48) | CCKBRCCKAR | |
| SCHEMBL8535348 | 0.81 | TP53 (0.42) | CCKBRCCKAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5763437-A | Benzodiazepine derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-06-09 | — | — | US | disclosed |