Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 2/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7018288 | 0.75 | NAAA (0.50) | NAAAPOLBHPGDSMN1; SMN2FKBP1A | |
| SCHEMBL18748460 | 0.74 | FAAH (0.42) | NAAAPOLBHPGDSMN1; SMN2FKBP1A | |
| SCHEMBL8960581 | 0.73 | NAAA (0.48) | NAAAPOLBHPGDSMN1; SMN2FKBP1A | |
| SCHEMBL7296671 | 0.73 | NAAA (0.48) | NAAAPOLBHPGDSMN1; SMN2FKBP1A | |
| SCHEMBL8070471 | 0.72 | NAAA (0.47) | NAAAPOLBHPGDSMN1; SMN2FKBP1A | |
| SCHEMBL8537004 | 0.69 | TNKS (0.46) | — | |
| SCHEMBL25173231 | 0.69 | HDAC3 (0.36) | NAAASMN1; SMN2 | |
| SCHEMBL25173230 | 0.69 | HDAC3 (0.36) | NAAASMN1; SMN2 | |
| SCHEMBL475580 | 0.68 | NAAA (0.58) | NAAAFKBP1ANPC1TDP1FAAH | |
| SCHEMBL475582 | 0.68 | NAAA (0.58) | NAAAFKBP1ANPC1TDP1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5801249-A | Chiral auxiliaries | OXFORD ASYMMETRY INTERNATIONAL PLC (GB) | 1998-09-01 | — | — | US | disclosed |
| EP-0736017-A1 | IMPROVEMENTS IN OR RELATING TO CHIRAL AUXILIARIES | OXFORD ASYMMETRY LIMITED (GB) | 1996-10-09 | — | — | EP | disclosed |
| WO-1995018112-A1 | IMPROVEMENTS IN OR RELATING TO CHIRAL AUXILIARIES | OXFORD ASYMMETRY LIMITED (GB) | 1995-07-06 | — | — | WO | disclosed |