Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 2/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8960479 | 0.84 | L3MBTL1 (0.46) | NAAAHPGDSMN1; SMN2NPC1TDP1 | |
| SCHEMBL8960322 | 0.78 | ALDH1A1 (0.36) | NAAAPOLBALDH1A1S1PR1 | |
| SCHEMBL8537851 | 0.73 | NAAA (0.48) | NAAAHPGDSMN1; SMN2NPC1TDP1 | |
| SCHEMBL7018288 | 0.72 | NAAA (0.50) | NAAAHPGDSMN1; SMN2NPC1TDP1 | |
| SCHEMBL8960315 | 0.71 | SMN1; SMN2 (0.46) | SMN1; SMN2L3MBTL1POLB | |
| SCHEMBL8696408 | 0.68 | HPGD (0.63) | HPGDSMN1; SMN2NPC1TDP1POLB | |
| SCHEMBL7296671 | 0.68 | NAAA (0.48) | NAAAHPGDSMN1; SMN2NPC1TDP1 | |
| SCHEMBL14028152 | 0.67 | POLB (0.73) | NAAAHPGDSMN1; SMN2NPC1TDP1 | |
| SCHEMBL8070471 | 0.67 | NAAA (0.47) | NAAAHPGDSMN1; SMN2NPC1TDP1 | |
| SCHEMBL21674867 | 0.66 | BRD4 (0.61) | HPGDSMN1; SMN2NPC1TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0693058-A1 | IMPROVEMENTS IN OR RELATING TO CHIRAL AUXILIARIES | OXFORD ASYMMETRY LIMITED (GB) | 1996-01-24 | — | — | EP | disclosed |
| WO-1994024104-A1 | IMPROVEMENTS IN OR RELATING TO CHIRAL AUXILIARIES | OXFORD ASYMMETRY LIMITED (GB) | 1994-10-27 | — | — | WO | disclosed |