Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | MC4R | P32245 | 1/20 | 0.37 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.35 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8537988 | 1.00 | ALDH1A1 (0.41) | ALDH1A1DDB1CRBNTSHRCHRM2 | |
| SCHEMBL8536576 | 1.00 | ALDH1A1 (0.41) | ALDH1A1DDB1CRBNTSHRCHRM2 | |
| SCHEMBL8536582 | 1.00 | ALDH1A1 (0.41) | ALDH1A1DDB1CRBNTSHRCHRM2 | |
| SCHEMBL8536369 | 0.99 | ALDH1A1 (0.42) | ALDH1A1DDB1CRBNTSHRCHRM2 | |
| SCHEMBL8536373 | 0.99 | ALDH1A1 (0.42) | ALDH1A1DDB1CRBNTSHRCHRM2 | |
| SCHEMBL8726547 | 0.79 | GABRA1 (0.42) | ALDH1A1TSHRHPGDHSD17B10GAA | |
| SCHEMBL8537085 | 0.79 | NOS2 (0.38) | ALDH1A1TSHRHPGDHSD17B10GAA | |
| SCHEMBL4701849 | 0.79 | NOS2 (0.38) | ALDH1A1TSHRHPGDHSD17B10GAA | |
| SCHEMBL8537088 | 0.79 | NOS2 (0.38) | ALDH1A1TSHRHPGDHSD17B10GAA | |
| SCHEMBL8532921 | 0.78 | NOS2 (0.38) | ALDH1A1TSHRHPGDHSD17B10GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5763437-A | Benzodiazepine derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-06-09 | — | — | US | disclosed |
| EP-0804425-A2 | BENZODIAZEPINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-11-05 | — | — | EP | disclosed |