Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK2 | O00142 | 4/20 | 0.42 |
| ▸ | TK1 | P04183 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ALB | P02768 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | TYMP | P19971 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9538710 | 0.91 | TK2 (0.35) | TK2TK1ALDH1A1LMNAALB | |
| SCHEMBL3300461 | 0.88 | TK2 (0.38) | TK2TK1TYMP | |
| SCHEMBL16267750 | 0.82 | SLC28A1 (0.41) | — | |
| SCHEMBL8744204 | 0.81 | TK1 (0.40) | TK2TK1ALDH1A1LMNAALB | |
| SCHEMBL8859645 | 0.79 | TK2 (0.36) | TK2TK1ALDH1A1LMNAALB | |
| SCHEMBL8987848 | 0.78 | TK1 (0.36) | TK2TK1ALDH1A1LMNAALB | |
| SCHEMBL28182722 | 0.76 | TK2 (0.46) | TK2TK1ALDH1A1LMNAALB | |
| SCHEMBL22345897 | 0.75 | TK1 (0.40) | TK2TK1ALDH1A1LMNAALB | |
| SCHEMBL3797592 | 0.75 | TK1 (0.40) | TK2TK1ALDH1A1LMNAALB | |
| SCHEMBL28190357 | 0.75 | TK2 (0.47) | TK2TK1ALDH1A1LMNAALB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108779138-A | Design and synthesis of nucleotides based on novel disulfide linkers for use as reversible terminators for DNA sequencing by synthesis | 哥伦比亚大学董事会 | 2018-11-09 | — | — | CN | disclosed |
| CN-102030792-B | 3'-o-fluorescently modified nucleotides and uses thereof | KOREA INST SCI & TECH | 2014-09-24 | — | — | CN | disclosed |
| CN-102030792-A | 3'-o-fluorescently modified nucleotides and uses thereof | KOREA INST SCI & TECH | 2011-04-27 | — | — | CN | disclosed |
| EP-0836612-A1 | NOVEL SYNTHONS FOR STEREOSELECTIVE OLIGONUCLEOTIDE SYNTHESIS | HYBRIDON, Inc. (US) | 1998-04-22 | — | — | EP | disclosed |
| EP-0753002-A1 | MODIFIED OLIGONUCLEOTIDES AND INTERMEDIATES USEFUL IN NUCLEIC ACID THERAPEUTICS | AMGEN INC. (US) | 1997-01-15 | — | — | EP | disclosed |
| WO-1996037504-A1 | NOVEL SYNTHONS FOR STEREOSELECTIVE OLIGONUCLEOTIDE SYNTHESIS | HYBRIDON, INC. (US) | 1996-11-28 | — | — | WO | disclosed |
| EP-0707591-A1 | METHYLPHOSPHONIC ACID ESTER, PROCESS FOR PREPARING THE SAME AND ITS USE | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-04-24 | — | — | EP | disclosed |
| WO-1995026972-A1 | MODIFIED OLIGONUCLEOTIDES AND INTERMEDIATES USEFUL IN NUCLEIC ACID THERAPEUTICS | AMGEN INC. (US) | 1995-10-12 | — | — | WO | disclosed |
| WO-1994022893-A1 | OLIGONUCLEOSIDE LINKAGES CONTAINING ADJACENT NITROGEN ATOMS | ISIS PHARMACEUTICALS, INC. (US) | 1994-10-13 | — | — | WO | disclosed |
| WO-1994022883-A1 | BACKBONE MODIFIED OLIGONUCLEOTIDES AND THEIR PREPARATION | ISIS PHARMACEUTICALS, INC. (US) | 1994-10-13 | — | — | WO | disclosed |
| WO-1994022454-A1 | OLIGONUCLEOSIDE LINKAGES CONTAINING ADJACENT OXYGEN AND NITROGEN ATOMS | ISIS PHARMACEUTICALS, INC. (US) | 1994-10-13 | — | — | WO | disclosed |
| EP-0064796-B1 | PHOSPHORYLATING AGENT AND PROCESS FOR THE PHOSPHORYLATION OF ORGANIC HYDROXYL COMPOUNDS | UNILEVER N.V. (NL) | 1985-05-15 | — | — | EP | disclosed |