Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 5/20 | 0.40 |
| ▸ | TK2 | O00142 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | ALB | P02768 | 2/20 | 0.37 |
| ▸ | BLM | P54132 | 2/20 | 0.37 |
| ▸ | TYMP | P19971 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8987848 | 0.90 | TK1 (0.36) | TK1TK2LMNAALBBLM | |
| SCHEMBL8744146 | 0.87 | TK1 (0.39) | TK1LMNATSHRALBBLM | |
| SCHEMBL9396549 | 0.86 | RNASE1 (0.39) | TK1TK2 | |
| SCHEMBL8744160 | 0.83 | TK1 (0.36) | TK1TK2TYMP | |
| SCHEMBL7776582 | 0.82 | SLC28A1 (0.42) | — | |
| SCHEMBL8538169 | 0.81 | TK2 (0.42) | TK1TK2LMNAALBBLM | |
| SCHEMBL28293120 | 0.78 | LMNA (0.36) | TK1TK2LMNAADRA1A | |
| SCHEMBL9216459 | 0.78 | ALDH1A1 (0.35) | TK1TK2LMNAALBBLM | |
| SCHEMBL28294848 | 0.76 | ALDH1A1 (0.34) | TK1TK2ALDH1A1 | |
| SCHEMBL28991368 | 0.76 | LMNA (0.36) | TK1TK2LMNAADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109661232-A | NUCLEOTIDE DERIVATIVES AND METHODS OF USE THEREOF | 纽约哥伦比亚大学董事会 | 2019-04-19 | — | — | CN | disclosed |
| CN-108779138-A | Design and synthesis of nucleotides based on novel disulfide linkers for use as reversible terminators for DNA sequencing by synthesis | 哥伦比亚大学董事会 | 2018-11-09 | — | — | CN | disclosed |
| EP-0753002-A1 | MODIFIED OLIGONUCLEOTIDES AND INTERMEDIATES USEFUL IN NUCLEIC ACID THERAPEUTICS | AMGEN INC. (US) | 1997-01-15 | — | — | EP | disclosed |
| WO-1995026972-A1 | MODIFIED OLIGONUCLEOTIDES AND INTERMEDIATES USEFUL IN NUCLEIC ACID THERAPEUTICS | AMGEN INC. (US) | 1995-10-12 | — | — | WO | disclosed |