Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK2 | O00142 | 4/20 | 0.35 |
| ▸ | TK1 | P04183 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ALB | P02768 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8538169 | 0.91 | TK2 (0.42) | TK2TK1ALDH1A1LMNAALB | |
| SCHEMBL3300461 | 0.81 | TK2 (0.38) | TK2TK1 | |
| SCHEMBL16267750 | 0.73 | SLC28A1 (0.41) | — | |
| SCHEMBL8859645 | 0.72 | TK2 (0.36) | TK2TK1ALDH1A1LMNAALB | |
| SCHEMBL28293078 | 0.72 | TK1 (0.32) | TK2TK1ALDH1A1NPSR1 | |
| SCHEMBL8744204 | 0.72 | TK1 (0.40) | TK2TK1ALDH1A1LMNAALB | |
| SCHEMBL9216459 | 0.71 | ALDH1A1 (0.35) | TK2TK1ALDH1A1NPSR1LMNA | |
| SCHEMBL28294848 | 0.70 | ALDH1A1 (0.34) | TK2TK1ALDH1A1NPSR1 | |
| SCHEMBL8987848 | 0.69 | TK1 (0.36) | TK2TK1ALDH1A1LMNAALB | |
| SCHEMBL28182722 | 0.67 | TK2 (0.46) | TK2TK1ALDH1A1LMNAALB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0541722-A1 | COMPOUNDS AND METHODS FOR INHIBITING GENE EXPRESSION. | STERLING WINTHROP INC (US) | 1993-05-19 | — | — | EP | disclosed |