Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8537834 | 0.96 | SLC9A1 (0.43) | SLC9A1THRB | |
| SCHEMBL8542861 | 0.95 | THRB (0.43) | SLC9A1THRB | |
| SCHEMBL8542373 | 0.92 | SLC9A1 (0.46) | SLC9A1 | |
| SCHEMBL8542629 | 0.86 | THRB (0.39) | SLC9A1THRB | |
| SCHEMBL6719348 | 0.83 | SLC9A1 (0.57) | SLC9A1 | |
| SCHEMBL8541278 | 0.82 | THRB (0.44) | THRB | |
| SCHEMBL8542394 | 0.81 | THRB (0.46) | THRB | |
| SCHEMBL8538604 | 0.81 | SLC9A1 (0.73) | SLC9A1 | |
| SCHEMBL8539475 | 0.80 | THRB (0.35) | THRB | |
| SCHEMBL8543433 | 0.79 | TXNRD1 (0.39) | THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5744641-A | Sulfonyl- or sulfinylbenzoylguanidine derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-04-28 | — | — | US | disclosed |