Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.51 |
| ▸ | S1PR1 | P21453 | 8/20 | 0.50 |
| ▸ | S1PR3 | Q99500 | 6/20 | 0.50 |
| ▸ | S1PR5 | Q9H228 | 4/20 | 0.50 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.46 |
| ▸ | S1PR4 | O95977 | 3/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8499108 | 0.89 | S1PR1 (0.53) | S1PR1S1PR3S1PR5PLA2G4BS1PR4 | |
| SCHEMBL8499033 | 0.89 | S1PR1 (0.53) | S1PR1S1PR3S1PR5PLA2G4BS1PR4 | |
| SCHEMBL8740051 | 0.88 | L3MBTL1 (0.49) | S1PR1S1PR3S1PR5 | |
| SCHEMBL8535031 | 0.88 | S1PR1 (0.42) | S1PR1S1PR3S1PR5S1PR4 | |
| SCHEMBL8500326 | 0.88 | FFAR1 (0.50) | FFAR1 | |
| SCHEMBL8499547 | 0.88 | S1PR1 (0.51) | S1PR1S1PR3S1PR5S1PR4 | |
| SCHEMBL8496364 | 0.87 | S1PR1 (0.48) | S1PR1S1PR3S1PR5S1PR4 | |
| SCHEMBL8499845 | 0.87 | ALDH1A1 (0.46) | S1PR1S1PR3S1PR5S1PR4 | |
| SCHEMBL8496246 | 0.86 | ALDH1A1 (0.43) | — | |
| SCHEMBL8499772 | 0.86 | ALDH1A1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0627406-B1 | 2-AMINO-1,3-PROPANEDIOL COMPOUND AND IMMUNOSUPPRESSANT | YOSHITOMI PHARMACEUTICAL (JP) | 1998-10-28 | — | — | EP | disclosed |
| US-5604229-A | 2-amino-1,3-propanediol compound and immunosuppressant | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-02-18 | — | — | US | disclosed |
| EP-0627406-A1 | 2-AMINO-1,3-PROPANEDIOL COMPOUND AND IMMUNOSUPPRESSANT | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1994-12-07 | — | — | EP | disclosed |