Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HMGCR | P04035 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9265819 | 1.00 | ALDH1A1 (0.45) | ALDH1A1TDP1LMNACA2GPR84 | |
| SCHEMBL9263902 | 1.00 | ALDH1A1 (0.45) | ALDH1A1TDP1LMNACA2GPR84 | |
| SCHEMBL9265047 | 0.96 | ALDH1A1 (0.50) | ALDH1A1TDP1LMNACA2GPR84 | |
| SCHEMBL9257086 | 0.92 | ALDH1A1 (0.45) | ALDH1A1TDP1LMNACA2GPR84 | |
| SCHEMBL1191304 | 0.91 | LMNA (0.48) | LMNAGPR84FFAR1MAPTHMGCR | |
| SCHEMBL17392527 | 0.91 | LMNA (0.48) | LMNAGPR84FFAR1MAPTHMGCR | |
| SCHEMBL5057383 | 0.91 | LMNA (0.48) | LMNAGPR84FFAR1MAPTHMGCR | |
| SCHEMBL459538 | 0.91 | LMNA (0.48) | LMNAGPR84FFAR1MAPTHMGCR | |
| SCHEMBL9466956 | 0.89 | FAAH (0.44) | TDP1LMNAFFAR1MAPTCYP3A4 | |
| SCHEMBL1826402 | 0.89 | ALDH1A1 (0.46) | ALDH1A1TDP1LMNACA2GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5747066-A | PHOSPHATIDES, BILE ACID SALT OR DIHEXANOYLLECITHIN | HOFFMANN-LA ROCHE INC. (US) | 1998-05-05 | — | — | US | disclosed |