Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.35 |
| ▸ | BAD | Q92934 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CCR5 | P51681 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25630937 | 0.78 | BCL2L1 (0.36) | BCL2L1BADCES1ALDH1A1NOS3 | |
| SCHEMBL30496031 | 0.76 | BCL2L1 (0.35) | BCL2L1BADALDH1A1NOS3NOS1 | |
| SCHEMBL26083963 | 0.76 | BCL2L1 (0.35) | BCL2L1BADCES1ALDH1A1NOS3 | |
| SCHEMBL10157474 | 0.76 | BCL2L1 (0.35) | BCL2L1BADALDH1A1NOS3NOS1 | |
| SCHEMBL13499974 | 0.73 | BCL2L1 (0.32) | BCL2L1BADCES1ALDH1A1NOS3 | |
| SCHEMBL25672212 | 0.73 | LMNA (0.37) | BCL2L1BADCES1ALDH1A1NOS3 | |
| SCHEMBL9449696 | 0.69 | CCR5 (0.30) | CCR5 | |
| SCHEMBL667046 | 0.64 | CCR5 (0.33) | NOS3NOS2CCR5 | |
| SCHEMBL1278375 | 0.64 | BCL2L1 (0.52) | BCL2L1BADCES1NOS3NOS1 | |
| SCHEMBL3803913 | 0.64 | DRD4 (0.32) | DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5763437-A | Benzodiazepine derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-06-09 | — | — | US | disclosed |
| EP-0804425-A2 | BENZODIAZEPINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-11-05 | — | — | EP | disclosed |
| WO-1996004254-A2 | BENZODIAZEPINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-02-15 | — | — | WO | disclosed |