Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8263271 | 0.78 | PARP1 (0.34) | — | |
| SCHEMBL23782700 | 0.77 | ADRA1A (0.37) | — | |
| SCHEMBL16420391 | 0.73 | — | — | |
| SCHEMBL16420393 | 0.73 | GPR84 (0.32) | — | |
| SCHEMBL18152992 | 0.73 | BCL2L1 (0.35) | — | |
| SCHEMBL526715 | 0.73 | ALDH1A1 (0.36) | — | |
| SCHEMBL17144450 | 0.73 | ADRA1A (0.37) | — | |
| SCHEMBL15680323 | 0.72 | — | — | |
| SCHEMBL8538260 | 0.69 | BCL2L1 (0.35) | CCR5 | |
| SCHEMBL21485338 | 0.67 | ADRA1A (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5194439-A | 5-HT Agonists or Antagonists, Nervous System Disorders, Hypotensive Agents | JOHN WYETH & BROTHER LIMITED (GB) | 1993-03-16 | — | — | US | disclosed |
| US-5075303-A | Central nervous system disorders | JOHN WYETH & BROTHER LIMITED (GB) | 1991-12-24 | — | — | US | disclosed |