Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 1/20 | 0.35 |
| ▸ | SLC9A1 | P19634 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.33 |
| ▸ | CNR2 | P34972 | 4/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | DDR1 | Q08345 | 2/20 | 0.30 |
| ▸ | ELOVL6 | Q9H5J4 | 1/20 | 0.30 |
| ▸ | CCR8 | P51685 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8540494 | 0.95 | CA12 (0.35) | CCR2SLC9A1KCNH2EPHX2CNR2 | |
| SCHEMBL8537147 | 0.95 | CA12 (0.33) | CCR2SLC9A1KCNH2EPHX2CNR2 | |
| SCHEMBL8544558 | 0.94 | CA12 (0.37) | EPHX2CNR2DDR1 | |
| SCHEMBL8543067 | 0.94 | CA12 (0.37) | EPHX2CNR2DDR1 | |
| SCHEMBL8538912 | 0.84 | CCR2 (0.34) | CCR2EPHX2CNR2CTSSDDR1 | |
| SCHEMBL8541311 | 0.83 | TAS1R3 (0.34) | SLC9A1KCNH2EPHX2CNR2HCRTR1 | |
| SCHEMBL8541951 | 0.81 | SLC9A1 (0.41) | SLC9A1 | |
| SCHEMBL6937870 | 0.81 | SLC9A1 (0.54) | SLC9A1KCNH2 | |
| SCHEMBL8536966 | 0.80 | CNR2 (0.32) | SLC9A1CNR2KMT2A | |
| SCHEMBL8543281 | 0.80 | CA12 (0.37) | DDR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5744641-A | Sulfonyl- or sulfinylbenzoylguanidine derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-04-28 | — | — | US | disclosed |