Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22181066 | 0.80 | TERT (0.50) | TERTALDH1A1HDAC8HDAC6RECQL | |
| SCHEMBL8540408 | 0.79 | TPMT (0.39) | ALDH1A1POLBHDAC8HDAC6HSD17B10 | |
| SCHEMBL2860049 | 0.78 | PARP1 (0.52) | TERTALDH1A1HDAC8HDAC6HSD17B10 | |
| SCHEMBL11688270 | 0.78 | TERT (0.49) | TERTHDAC8HDAC6RECQLL3MBTL1 | |
| SCHEMBL8538803 | 0.77 | TERT (0.48) | TERTALDH1A1HSD17B10PARP1KMT2A | |
| SCHEMBL22852718 | 0.76 | TERT (0.47) | TERTALDH1A1HDAC8HDAC6RECQL | |
| SCHEMBL13415413 | 0.76 | TERT (0.54) | TERTALDH1A1POLBHDAC8HDAC6 | |
| SCHEMBL11662577 | 0.75 | TERT (0.41) | TERTALDH1A1POLBHDAC8HDAC6 | |
| SCHEMBL24523122 | 0.74 | FFAR1 (0.48) | ALDH1A1HDAC8HDAC6RECQLHSD17B10 | |
| SCHEMBL15199707 | 0.74 | TERT (0.49) | TERTPOLBHDAC8HDAC6HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5808062-A | AIDS THERAPY | WARNER-LAMBERT COMPANY (US) | 1998-09-15 | — | — | US | disclosed |